Results 191 to 200 of about 28,979,637 (350)

Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis

Molecular Oncology, EarlyView.
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini, Maria Caterina Mione   +1 more
wiley   +1 more source

Visualizing Complex Problems in Leadership Education: A System Dynamics Perspective. [PDF]

New Dir Stud Leadersh
Goodwin CM, Marzolino TA.
europepmc   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Time Series Prediction of Open Quantum System Dynamics by Transformer Neural Networks. [PDF]

Entropy (Basel)
Wang ZW, Wu LA, Wang ZM.
europepmc   +1 more source

Organizational size, flexibility, and performance---A system dynamics approach

, 2009
補正完畢國內20010723 ...
韓釗; Han, Charles C.
core  

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Market system dynamics

, 2017
M. Giesler, Eileen Fischer
semanticscholar   +1 more source

Cost-effectiveness of 6-year school-based caries preventive interventions in Thailand: a system dynamics modeling study. [PDF]

Front Public Health
Oo TH, Thitasomakul S, Sontamino P, Tianviwat S.   +3 more
europepmc   +1 more source

Sustainable Governance of Global Navigation Satellite System (GNSS) Continuously Operating Reference Station (CORS) Infrastructure

, 2018
Acquiring a precise position on the earth is an essential factor in many activities today and will be a prerequisite for future activities. Global Navigation Satellite System (GNSS) Continuously Operating Reference Station (CORS) network or GNSS CORS is ...
Supinajaroen, W. (author), van Loenen, B. (author)   +1 more
core  

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source