Results 41 to 50 of about 18,012,949 (286)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

The development of a hybrid intelligent maintenance optimisation system (HIMOS).

, 2001
This paper reports on the development of a hybrid intelligent maintenance optimisation system (HIMOS) for decision support. It is a follow-up to an earlier paper published in the Journal of the Operational Research Society in 1995.
Jeon, J, Kobbacy, KAH
core   +1 more source

A Review of State-of-the-Art Developments in Large-Scale Photovoltaic Solar Renewable Energy Systems

Journal of Engineering
This paper provides a comprehensive review of recent advancements in large-scale photovoltaic (PV) systems, covering technological innovations, optimization strategies, power converter integration methods, and challenges in monitoring and maintenance ...
Lyu Guanghua, Syed Hadi Hussain Shah, Asad A. Zaidi, Faisal Nawaz, Sohaib Z. Khan   +4 more
doaj   +1 more source

2DOF-PID-TD: A new hybrid control approach of load frequency control in an interconnected thermal-hydro power system

Heliyon
The Load Frequency Control (LFC) scheme, with its primary aim being the maintenance of uniform frequency, has been a heavily researched topic for decades.
Md. Nazmush Shakib Shahi, Nabil Anan Orka, Ashik Ahmed   +2 more
doaj   +1 more source

Optimal Combination and Sizing of a Stand–Alone Hybrid Energy System Using a Nomadic People Optimizer

IEEE Access, 2020
In this work, the main objective is the provision of an electric supply to a residential complex located in a remote area in Iraq (Thi-Qar) that has no access to the electricity grid.
Abbas Q. Mohammed, Kassim A. Al-Anbarri, Rafid M. Hannun   +2 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Multi-criteria decision model for multicircular flight control of unmanned aerial vehicles through a hybrid approach

Scientific Reports
This study presents a novel approach for optimizing UAV (unmanned aerial vehicle) Multicircular flight control by developing a fractional order proportional integral derivative (FOPID)-based hybrid Eagle strategy particle swarm optimization ant lion ...
Noorulden Basil, Hamzah M. Marhoon, Bayan Mahdi Sabbar, Abdullah Fadhil Mohammed, Osamah Albahri, Ahmed Albahri, Abdullah Alamoodi, Iman Mohamad Sharaf, Amare Merfo Amsal, Mahrous Ahmed, Enas Ali, Sherif S. M. Ghoneim   +11 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Maintenance optimisation of a parallel-series system with stochastic and economic dependence under limited maintenance capacity

, 2016
Maintenance optimisation of a parallel-series system considering both stochastic and economic dependence among components as well as limited maintenance capacity is studied in this paper. The maintenance strategies of the components are jointly optimised,
Sun, Yong, Ma, Lin, Zhou, Yifan, Lin, Tian Ran   +3 more
core   +1 more source