Results 61 to 70 of about 18,012,949 (286)

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Optimal Maintenance Policy for a Markov Deteriorating System Under Reliability Limit

In this study, failure data of computer numerical control machine used in defense industry was analyzed to develop maintenance algorithm with a Markov feature. An imperfect preventive maintenance model that minimizes long-term operational cost is created
Khaniyev, Tahir, Ozturk, Meltem Kocer
core   +1 more source

Smart Energy Strategy for AC Microgrids to Enhance Economic Performance in Grid-Connected and Standalone Operations: A Gray Wolf Optimizer Approach

Sci
This study proposes an optimized energy management strategy for alternating current microgrids, integrating wind generation, battery energy storage systems (BESSs), and distribution static synchronous compensators (D-STATCOMs).
Sebastian Lobos-Cornejo, Luis Fernando Grisales-Noreña, Fabio Andrade, Oscar Danilo Montoya, Daniel Sanin-Villa   +4 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Photovoltaic array fault diagnosis and dynamic reconfiguration based on improved YOLOv7 and QAGO

Discover Computing
The rapid expansion of photovoltaic power generation increases the difficulty of maintaining stable performance, because traditional operation and maintenance methods cannot handle the efficiency loss caused by array faults.
Yongliang Luo, Xuwen Zheng, Biao Yang
doaj   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

A Parallel Adapted AJAYA-Based BESS Energy Management System Under Energy Uncertainty for Reducing Operating, Maintenance, and Degradation Costs in ADNs

Electricity
Active distribution networks (ADNs) require battery energy storage system (BESS) scheduling strategies that reduce operating costs while preserving electrical feasibility and battery lifetime. This paper proposes a parallel adapted JAYA-based methodology
Luis Fernando Grisales-Noreña, Oscar Danilo Montoya, Víctor Manuel Garrido-Arévalo   +2 more
doaj   +1 more source

Optimization of maintenance system

, 2013
This report presents an optimization of the allocation of maintenance resources for Air Navigation Service (ANS) equipment of which LFV is responsible for the maintenance. The purpose the authors have worked after is to research ways of minimizing travelling time linked to maintenance visits for ANS equipment, this report includes the suggestions where
Andersson, Matilda, Wandfelt, Fredrik
openaire   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source