Results 51 to 60 of about 18,012,949 (286)
, 2022 In this research, we introduce an artificial gorilla troop optimizer for use in artificial neural networks that manage energy consumption in DC–AC hybrid distribution networks.
Mohana Jaishankar +2 more
core +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Optimization of maintenance management of trees in powerdistribution systems
Revista Tecnura, 2013 We propose a data-analysis-based methodology for maintaining trees that affect power distribution networks. From the information captured in the field, we use fuzzy-logic-based techniques and models together with genetic algorithms so as to focus maintenance activities on the optimal time and place.
Martínez, José Alexander +1 more
openaire +4 more sources
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Informatics in Medicine UnlockedThe optimization of the vaccination campaign and medication distribution in rural regions of Morocco conducted by the Ministry of Health can be significantly improved by employing metaheuristic algorithms in conjunction with a tour planning system.
Toufik Mzili +6 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Scientific ReportsAccurate regulation of the liquid level in a quadruple tank system (QTS) is not easy and imposes higher requirements on control strategies, so the design of controllers in these systems is challenging due to the difficulty of dynamic analysis of its ...
Faycal Medjili +7 more
doaj +1 more source
Cost optimal maintenance in systems with imperfect maintenance
, 2016 von Dipl.-Wirtsch.-Math.
openaire +2 more sources
Optimal Maintenance of a Production System with L Intermediate Buffers [PDF]
Mathematical Problems in Engineering, 2012 We consider a production‐inventory system that consists of an input‐generating installation, a production unit and L intermediate buffers. It is assumed that the installation transfers the raw material j ∈ {1, …, L} to buffer Bj, and the production unit pulls the raw material j ∈ {1, …, L} from buffer Bj.
Karamatsoukis, Constantinos C. +1 more
openaire +2 more sources