Results 161 to 170 of about 2,250,860 (287)

Quantitative datasets of societal value, technology and policy for human-water system modelling. [PDF]

Sci Data
Wu S, Wei Y, Wei J, Xiong Y, Huang S, Werdiningtyas R, Genova P, Hong P, Gan L, Song C.   +9 more
europepmc   +1 more source

Modelling System Administration Problems with CSPs [PDF]

, 2011
Anderson, Paul, Hewson, John
core  

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Empowering Indonesia's energy transition planning through long-term energy system modelling: A technoeconomic dataset. [PDF]

Data Brief
Irbah MRN, Slade R, Howells M, Fields N, Plazas-Niño FA, Richardson E.   +5 more
europepmc   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Assessment of Sleep-wake State-associated Dynamic Changes in Heart Rate Variability in Female Rat: Autonomic System Modelling Approaches for Studying Behavioural Dysregulation. [PDF]

Ann Neurosci
Va A, Namboodiri N, Gulia KK.
europepmc   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Correction: Kalmag: a high spatio-temporal model of the geomagnetic field

Earth, Planets and Space
Julien Baerenzung, Matthias Holschneider, Jan Saynisch-Wagner, Maik Thomas   +3 more
doaj   +1 more source

Explainable and generalizable AI-driven multiscale informatics for dynamic system modelling. [PDF]

Sci Rep
Luo C, Li AJ, Xiao J, Li M, Li Y.
europepmc   +1 more source