Results 91 to 100 of about 1,849,805 (333)
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Solutions Of The System Of Maximum Difference Equations
MANAS: Journal of Engineering, 2014 The behaviour of the solutions of the following system of difference equations is examined.
Dağıstan Şimşek, Ahmet Doğan
doaj
On a multidimensional close-to-cyclic system of difference equations
Miskolc Mathematical NotesThis paper investigates the solvability and dynamic properties of the following multidimensional close-to-cyclic system of nonlinear difference equations yn+1 (i)=aiyn (i+1) (y n−k (i+1))pi+1+b i (yn−k+1 (i))pi;n∈ℕ0,yn (i+k)=yn (i),pi+k=pi,ai+k=ai,bi+
Yacine Halim +2 more
doaj +1 more source
On a system of difference equations of third order solved in closed form
Journal of Innovative Applied Mathematics and Computational Sciences, 2021 In this work, we show that the system of difference equations xn+1=(ayn-2xn-1yn+bxn-1yn-2+cyn-2+d)/(yn-2xn-1yn), yn+1=(axn-2yn-1xn+byn-1xn-2+cxn-2+d)/(xn-2yn-1xn), where n belongs to the set of positive integer numbers, x-2, x-1, x0, y-2, y-1 and y0 are ...
Youssouf AKROUR +2 more
doaj
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Solutions of the System of Maximum Difference Equations
MANAS: Journal of Engineering, 2016 The behaviour and periodicity of the solutions of the following system of difference equations is ...
D. Şimşek, M. Eröz, B. Öğul
doaj
On a System of Two High-Order Nonlinear Difference Equations
Advances in Mathematical Physics, 2014 This paper is concerned with dynamics of the solution to the system of two high-order nonlinear difference equations xn+1=xn-k/(q+∏i=0kyn-i), yn+1=yn-k/(p+∏i=0kxn-i), k∈N+, n=0,1,…, where p,q∈(0,∞), x-i∈(0,∞), y-i∈(0,∞) and i=0,1,…,k.
Qianhong Zhang, Wenzhuan Zhang
doaj +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source