Results 101 to 110 of about 1,849,805 (333)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Analytical Study of Nonlinear Systems of Higher-Order Difference Equations: Solutions, Stability, and Numerical Simulations

open access: yesMathematics
This paper aims to derive analytical expressions for solutions of fractional bidimensional systems of difference equations with higher-order terms under specific parametric conditions. Additionally, formulations of solutions for one-dimensional equations
Hashem Althagafi, Ahmed Ghezal
doaj   +1 more source

On consistent systems of difference equations [PDF]

open access: yesJournal of Physics A: Mathematical and Theoretical, 2019
We consider overdetermined systems of difference equations for a single function $u$ which are consistent, and propose a general framework for their analysis. The integrability of such systems is defined as the existence of higher order symmetries in both lattice directions and various examples are presented.
openaire   +4 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Global Dynamics of a 3 × 6 System of Difference Equations

open access: yesDiscrete Dynamics in Nature and Society, 2019
In the proposed work, global dynamics of a 3×6 system of rational difference equations has been studied in the interior of R+3. It is proved that system has at least one and at most seven boundary equilibria and a unique +ve equilibrium under certain ...
S. M. Qureshi, A. Q. Khan
doaj   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

On a System of Difference Equations of an Economic Model

open access: yesDiscrete Dynamics in Nature and Society, 2013
We study some qualitative properties of the solutions of a system of difference equations, which describes an economic model. The study of the local stability of the equilibrium points is carried out.
M. F. Elettreby, H. El-Metwally
doaj   +1 more source

Discontinuous Almost Automorphic Functions and Almost Automorphic Solutions of Differential Equations with Piecewise Constant Argument

open access: yes, 2013
In this article we introduce a class of discontinuous almost automorphic functions which appears naturally in the study of almost automorphic solutions of differential equations with piecewise constant argument.
Castillo, S., Chavez, A., Pinto, M.
core   +1 more source

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