Results 121 to 130 of about 1,849,805 (333)

On a k-Order System of Lyness-Type Difference Equations

Advances in Difference Equations, 2007
We consider the following system of Lyness-type difference equations: , , , , where , , , are positive constants, is an integer, and the initial values are positive real numbers.
Papaschinopoulos G, Schinas CJ, Stefanidou G   +2 more
doaj  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Solvability of Three-Dimensional Nonlinear Difference Systems via Transformations and Generalized Fibonacci Recursions

Mathematics
This paper presents closed-form solutions for a three-dimensional system of nonlinear difference equations with variable coefficients. The approach employs functional transformations and leverages generalized Fibonacci sequences to construct the ...
Yasser Almoteri, Ahmed Ghezal
doaj   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Algebraic Reduction and Periodic Solvability in a Coupled Ternary Rational System

Mathematics
In this paper, we investigate a new class of three-component nonlinear rational difference equations of the second order characterized by structured periodic interactions.
Ahmed Ghezal, Ahmed A. Al Ghafli, Hassan J. Al Salman   +2 more
doaj   +1 more source

Sticky Information and Determinacy [PDF]

The infinite-dimensional sticky-information Phillips curve is cast as a finite-dimensional timevarying system of difference equations in order to directly assess determinacy in the model with demand given by the forward-looking IS equation and monetary ...
Alexander Meyer-Gohde
core  

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Solvable product-type system of difference equations of second order

Electronic Journal of Differential Equations, 2015
We show that the system of difference equations $$ z_{n+1}=\frac{w_n^a}{z_{n-1}^b},\quad w_{n+1}=\frac{z_n^c}{w_{n-1}^d},\quad n\in\mathbb{N}_0, $$ where $a,b,c,d\in\mathbb{Z}$, and initial values $z_{-1}, z_0, w_{-1}, w_0\in\mathbb{C}$, is ...
Stevo Stevic, Mohammed A. Alghamdi, Abdullah Alotaibi, Elsayed M. Elsayed   +3 more
doaj  

NUMERICAL SOLUTION OF THE SYSTEM OF VOLTERRA INTEGRO-FRACTIONAL DIFFERENTIAL EQUATIONS BY USING FOURTH ORDER BLOCK-BY-BLOCK METHOD BASED ON THE FINITE DIFFERENCE APPROXIMATION

, 2023
José Rodrigo González Granada, Fernando Mesa, Germán Correa Vélez, José Rodrigo González Granada, Fernando Mesa, Germán Correa Vélez   +1 more
openalex   +2 more sources