Results 91 to 100 of about 313,126 (308)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

System of Linear Equations [PDF]

open access: yes, 2008
Students will solve systems of equations by graphing. Through using the graphing calculator students will be able to visually see how linear equations cross to create a solution to a system of equations.
Bruyea, Courtney
core   +1 more source

Interval solutions of linear interval equations [PDF]

open access: yes, 1990
summary:It is shown that if the concept of an interval solution to a system of linear interval equations given by Ratschek and Sauer is slightly modified, then only two nonlinear equations are to be solved to find a modified interval solution or to ...
Rohn, Jiří
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

A New System of Consumer Demand Equations [PDF]

open access: yes
This paper commences from a new indirect utility function and derives the corresponding system of equations, relating commodity demands to prices and income, that satisfies the constraints imposed by utility maximisation (aggregation, homogeneity ...
Prof. Denis Conniffe
core  

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Asymptotic behavior of a system of linear fractional difference equations

open access: yesJournal of Inequalities and Applications, 2005
We investigate the global asymptotic behavior of solutions of the system of difference equations , , , where the parameters , , , and are positive numbers and the initial conditions and are arbitrary nonnegative numbers.
Nurkanović M, Kulenović MRS
doaj  

On tau functions associated with linear systems [PDF]

open access: yes, 2012
\noindent {\bf Abstract} This paper considers the Fredholm determinant $\det (I-\Gamma_x)$ of a Hankel integral operator on $L^2(0, \infty )$ with kernel $\phi (s+t+2x)$, where $\phi$ is a matrix scattering function.
Samantha L. Newsham   +3 more
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

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