Results 81 to 90 of about 175,846,736 (289)

Solving Optimization Problems on Hermitian Matrix Functions with Applications

open access: yesJournal of Applied Mathematics, 2013
We consider the extremal inertias and ranks of the matrix expressions f(X,Y)=A3-B3X-(B3X)*-C3YD3-(C3YD3)*, where A3=A3*,   B3,   C3, and D3 are known matrices and Y and X are the solutions to the matrix equations A1Y=C1, YB1=D1, and A2X=C2, respectively.
Xiang Zhang, Shu-Wen Xiang
doaj   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

open access: yesFEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

The Optimization on Ranks and Inertias of a Quadratic Hermitian Matrix Function and Its Applications

open access: yesJournal of Applied Mathematics, 2013
We solve optimization problems on the ranks and inertias of the quadratic Hermitian matrix function subject to a consistent system of matrix equations and .
Yirong Yao
doaj   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

open access: yesFEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Solution of arbitrary fully fuzzy matrix equations and pair fully fuzzy matrix equations [PDF]

open access: yes, 2021
Control system theory often involved the application of matrix equations and pair matrix equations where there are possibilities that uncertainty conditions can exist.
Wan Suhana, Wan Daud
core   +1 more source

Modeling Flexible Bodies in Multibody Systems in Joint-Coordinates Formulation Using Spatial Algebra

open access: yesAdvances in Mechanical Engineering, 2014
This paper presents an efficient approach of using spatial algebra operator to formulate the kinematic and dynamic equations for developing capabilities to model flexible bodies within general purpose multibody dynamics solver.
Mohamed A. Omar
doaj   +1 more source

Selective elimination of quiescent cancer cells by dequalinium chloride via ROS‐mediated ferroptosis

open access: yesFEBS Open Bio, EarlyView.
Dequalinium chloride (DQ) selectively eliminates quiescent cancer cells (QCCs) by amplifying mitochondrial ROS. QCCs exhibit elevated basal ROS and limited redox‐buffering capacity, making them vulnerable to further ROS increases. DQ‐induced ROS exceeds the tolerance threshold, triggering lipid peroxidation and ferroptosis, whereas proliferating cells ...
Kotaro Miyamoto   +14 more
wiley   +1 more source

On iterative methods for some elliptic equations with nonlocal conditions

open access: yesNonlinear Analysis, 2014
The iterative methods for the solution of the system of the difference equations derived from the elliptic equation with nonlocal conditions are considered.
Olga Štikonienė   +2 more
doaj   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

open access: yesFEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao   +10 more
wiley   +1 more source

System of linear equations [PDF]

open access: yes, 1976
summary:The paper describes a method of solving the system of linear algebraic equations with a real rectangular matrix. The method is based on the use of the Gram-Schmidt orthogonalization.
Arora, J. L.
core   +1 more source

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