Results 231 to 240 of about 19,511,736 (306)

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Non-adiabatic effects in the photodissociation of H₂S.

Phys Chem Chem Phys
Perri AN, Mitrushchenkov AO, Yurchenko SN, Tennyson J.   +3 more
europepmc   +1 more source

MolScope: A Transparent Representation-Aware Workflow Toolkit for Reproducible Medicinal-Chemistry Triage. [PDF]

Mol Inform
Elokely KM.
europepmc   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Decolonizing Local Health: Advancing from Participation to Equitable Partnership along the Thailand-Myanmar Border. [PDF]

Ann Glob Health
Razak MH, Maung C.
europepmc   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source

Sound source localization for spatial mapping of surgical actions in dynamic scenes. [PDF]

Int J Comput Assist Radiol Surg
Hein J, Vlachopoulos L, Olthof MGL, Sigrist B, Fürnstahl P, Seibold M.   +5 more
europepmc   +1 more source

Ontology-based approaches for multi-destination tourism planning: a systematic literature review. [PDF]

Front Artif Intell
Izani UM, Che Lah NS.
europepmc   +1 more source

Correction: From chromosomal protein disorder to chromatin phase separation. [PDF]

Epigenetics Chromatin
Davie JR, Ausió J.
europepmc   +1 more source