Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Evaluasi Usability Aplikasi Tiket.com Menggunakan Metode System Usability Scale (SUS)
Studi ini berfokus pada evaluasi kegunaan platform pemesanan tiket online, Tiket.com, yang meskipun populer, telah menerima banyak ulasan negatif dari pengguna. Tujuan utama dari penelitian ini adalah untuk menilai kegunaan platform tersebut guna mengidentifikasi area perbaikan yang dapat meningkatkan pengalaman pengguna.
Via Alfilaeni +2 more
openaire +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
ANALISIS PERSEPSI USABILITY APLIKASI WHATSAPP BERDASARKAN SYSTEM USABILITY SCALE (SUS) [PDF]
Communication is one of the main characteristics of living beings that cannot be separated from daily life and is crucial in supporting human social life. With the advancement of information technology, communication methods have evolved from traditional
Fitrah Suryani Nasution, NIM.: 20106050042
core +1 more source
EVALUASI USABILITY APLIKASI WHATSAPP MENGGUNAKAN METODE SYSTEM USABILITY SCALE (SUS)
ABSTRACT WhatsApp has evolved from a platform for personal conversations into a communication space used for group coordination, document sharing, and information dissemination across various daily activities. Its widespread use does not necessarily reflect a uniform user experience; therefore, evaluating its usability is necessary to understand users’
M.Rizky Ramadhan +3 more
openaire +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
ANALISIS USABILITY PADA WEBSITE NAVIDOK MENGGUNAKAN METODE USABILITY TESTING DAN SYSTEM USABILITY SCALE (SUS) [PDF]
Pada era perkembangan teknologi saat ini semakin pesat dan memberikan dampak yang besar di berbagai bidang, salah satunya penggunaan website yang menjadi bagian penting dalam hal penyedia informasi.
Datu, Angela Liling
core
Metabolic syndrome is a cluster of risk factors for cardiovascular disease and type 2 diabetes mellitus in adults. The development of a health application-based instrument is important.
Okti Sri Purwanti +9 more
doaj +1 more source
A Turkish Translation of the System Usability Scale: The SUS-TR
Aim of developing usable and effective systems yield need for measuring quality of user experience with a system. The System Usability Scale (SUS) questionnaire that was developed in English has been widely used in the literature for assessing perceived usability of interactive systems. This study aimed to adapt the SUS into Turkish and investigate its
DEMİRKOL, Denizhan, ŞENELER, Çağla
openaire +1 more source

