Results 221 to 230 of about 19,487,049 (259)

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

Reply to: “Evaluating the Clinical Readiness of General-Purpose Large Language Models in Evidence Synthesis"

Spine Surgery and Related Research
Masaki Sakamoto, Shintaro Honda, Bungo Otsuki, Koichi Murata, Takayoshi Shimizu, Takashi Sono, Koichiro Shima, Takaki Yoshiyama, Ryohei Saito, Kosei Ono, Atsushi Tanaka, Shuichi Matsuda   +11 more
doaj  

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Rhupus: a systematic literature review

Autoimmunity Reviews, 2020
"Rhupus" or "rhupus syndrome" is a poorly described and underdiagnosed disease in which features of both rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) appear in the same patient, most often sequentially. The SLE-related involvement is usually mild, dominated by hematological abnormalities and skin, serosal and renal involvement.
Luca, Antonini, Brigitte, Le Mauff, Christian, Marcelli, Achille, Aouba, Hubert, de Boysson   +4 more
openaire   +2 more sources

Systematic literature reviews in software engineering – A systematic literature review

Information and Software Technology, 2009
Background: In 2004 the concept of evidence-based software engineering (EBSE) was introduced at the ICSE04 conference. Aims: This study assesses the impact of systematic literature reviews (SLRs) which are the recommended EBSE method for aggregating evidence.
Barbara A. Kitchenham, Pearl Brereton, David Budgen, Mark Turner 0001, John Bailey, Stephen G. Linkman   +5 more
openaire   +2 more sources

A Systematic Integrated Literature Review of Systematic Integrated Literature Reviews in Nursing

Journal of Nursing Education, 2012
As faculty members, we frequently find that first-year doctoral students in nursing are confused about how to conduct a systematic integrated literature review. This could be due to its vague definition and a lack of recent literature that provides directions for conducting a systematic integrated literature review.
Eun-Ok, Im, Sun Ju, Chang
openaire   +2 more sources

Repeatability of systematic literature reviews

15th Annual Conference on Evaluation & Assessment in Software Engineering (EASE 2011), 2011
Background: One of the anticipated benefits of systematic literature reviews (SLRs) is that they can be conducted in an auditable way to produce repeatable results. Aim: This study aims to identify under what conditions SLRs are likely to be stable, with respect to the primary studies selected, when used in software engineering.
Barbara A. Kitchenham, Pearl Brereton, Zhi Li 0017, David Budgen, Andrew James Burn   +4 more
openaire   +2 more sources

Systematic Literature Reviews

Journal of Obstetric, Gynecologic & Neonatal Nursing, 2009
Nancy K. Lowe, Editor Reviews of the literature play an important role in the advancement of nursing and biomedical science by combining the results of systematically chosen studies to come to conclusions about a body of research. The research literature on most topics pertinent to the care of women, infants, and their families is broad and ...
openaire   +2 more sources

Neurotoxocariasis: a systematic literature review

Infection, 2016
Toxocariasis is a widespread zoonosis, which may result in central nervous system injury.We conducted a systematic literature review in MEDLINE, SciELO, ScienceDirect and Google Scholar up to April 2015 using a combination of the following search terms: "neurotoxocariasis" or "neurotoxocarosis", "toxocariasis" or "toxocarosis" and "cerebral" or ...
Deshayes, S., Bonhomme, J., de La Blanchardière, Arnaud   +2 more
openaire   +3 more sources