Results 141 to 150 of about 535,118 (293)

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

A Novel Sea Target Tracking Algorithm for Multiple Unmanned Aerial Vehicles Considering Attitude Error in Low-Precision Geodetic Coordinate Environments

open access: yesAerospace
Geodetic coordinate information and attitude information of the observation platform are necessary for multi-UAV position alignment and target tracking. In a complex sea environment, the navigation equipment of a UAV is susceptible to interference.
Qiuyang Dai, Faxing Lu, Junfei Xu
doaj   +1 more source

Reseña: Noelie Rodríguez & Alan Ryave (2002). Systematic Self-Observation

open access: yes, 2002
Systematic Self-Observation vermittelt eine Zusammenschau der 13jährigen Arbeit der Autor(inn)en, indem sie die Chancen und Grenzen ihrer Methode der systematischen Selbstbeobachtung diskutieren.
Chaparro, Hernán
core   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Teacher appraisal : the impact of observation on teachers’ classroom behaviour [PDF]

open access: yes
This thesis is based on three English language teacher case studies located in the Middle East where classroom discourse has been analysed in order to establish the impact that an appraisal observer has on teachers‘ behaviour.
Howard, Amanda Jane
core  

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

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