Results 41 to 50 of about 6,467,255 (355)
Clinical trial registries can be used to monitor the production of trial evidence and signal when systematic reviews become out of date. However, this use has been limited to date due to the extensive manual review required to search for and screen ...
Bashir, Rabia +5 more
core +1 more source
The problems with systematic reviews: a living systematic review
Systematic reviews and meta-analyses are proliferating as they are an important building block to inform evidence-based guidelines and decision-making. Enforcement of best practice in clinical trials is firmly on the research agenda of good clinical practice, but there is less clarity as to how evidence syntheses that combine these studies can be ...
Uttley, L. +7 more
openaire +3 more sources
ABSTRACT Background Pediatric patients with extracranial solid tumors (ST) receiving chemotherapy are at an increased risk for Pneumocystis jirovecii pneumonia (PJP). However, evidence guiding prophylaxis practices in this population is limited. A PJP‐related fatality at our institution highlighted inconsistent prescribing approaches and concerns about
Kriti Kumar +8 more
wiley +1 more source
Objective: This study aimed to assess the efficacy and safety of various neoadjuvant regimens for patients diagnosed with early-stage or locally advanced triple-negative breast cancer (TNBC). Methods: Medline, EMBASE, Cochrane Library, and Web of Science
Junjie Li +6 more
doaj +1 more source
Digital Biomarker–Based Interventions: Systematic Review of Systematic Reviews
Background The introduction of new medical technologies such as sensors has accelerated the process of collecting patient data for relevant clinical decisions, which has led to the introduction of a new technology known as digital biomarkers.
Hossein Motahari-Nezhad +6 more
openaire +3 more sources
Psychosocial Outcomes in Patients With Endocrine Tumor Syndromes: A Systematic Review
ABSTRACT Introduction The combination of disease manifestations, the familial burden, and varying penetrance of endocrine tumor syndromes (ETSs) is unique. This review aimed to portray and summarize available data on psychosocial outcomes in patients with ETSs and explore gaps and opportunities for future research and care.
Daniël Zwerus +6 more
wiley +1 more source
Background Per- and polyfluoroalkyl substances (PFAS) were used or are being used in the manufacturing of products, including consumer-use products. The resulting environmental contamination has led to widespread human exposure.
Sebastian Hoffmann +4 more
doaj +1 more source
How reliable are systematic reviews in empirical software engineering? [PDF]
BACKGROUND – the systematic review is becoming a more commonly employed research instrument in empirical software engineering. Before undue reliance is placed on the outcomes of such reviews it would seem useful to consider the robustness of the ...
Kitchenham, BA +3 more
core +2 more sources
A systematic review of systematic reviews of homeopathy [PDF]
Homeopathy remains one of the most controversial subjects in therapeutics. This article is an attempt to clarify its effectiveness based on recent systematic reviews. Electronic databases were searched for systematic reviews/meta‐analysis on the subject. Seventeen articles fulfilled the inclusion/exclusion criteria.
openaire +2 more sources
Automation of systematic literature reviews: A systematic literature review
Abstract Context Systematic Literature Review (SLR) studies aim to identify relevant primary papers, extract the required data, analyze, and synthesize results to gain further and broader insight into the investigated domain. Multiple SLR studies have been conducted in several domains, such as software engineering, medicine, and pharmacy. Conducting
van Dinter, Raymon +2 more
openaire +4 more sources

