Results 181 to 190 of about 2,543,955 (363)

A scoping review of overview of reviews of nursing field in China

Huli yanjiu, 2021
CHEN Yu, HU Yan, ZHOU Yingfeng, XING Weijie, ZHU Zheng   +4 more
doaj  

The People’s Review protocol: planning an innovative study powered by the public

Research Involvement and Engagement
Background Systematic reviews provide the best quality evidence about the effectiveness of health treatments. However, systematic reviews and the important role they play in healthcare are not well understood beyond the walls of academia and healthcare ...
Éle Quinn, Shoba Dawson, Jeremy Holt, Shahed Hossain, Patricia Logullo, Ann O’Brien, Maureen Smith, Derek Stewart, Shaun Treweek, Charlene Young, Chris Noone, David Moher, Sinéad M. Hynes   +12 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

The impact of decentralisation on health systems: a systematic review of reviews. [PDF]

BMJ Glob Health, 2023
Sapkota S, Dhakal A, Rushton S, van Teijlingen E, Marahatta SB, Balen J, Lee AC, Nepal Federal Health System Team.   +7 more
europepmc   +1 more source

Nutritional Perspectives on Sickle Cell Disease in Africa: A Systematic Review

, 2020
Eunice Berko Nartey, Jonathan Spector, Seth Adu‐Afarwuah, Catherine L. Jones, Alan A. Jackson, Agartha Ohemeng, Rajiv Shah, Alice Koryo-Dabrah, Amma Benneh-Akwasi Kuma, Hyacinth I. Hyacinth, Matilda Steiner‐Asiedu   +10 more
openalex   +1 more source

A Plea for Minimally Biased Empirical Philosophy [PDF]

, 2017
Naturalistic philosophers rely on literature search and review in a number of ways and for different purposes. Yet this article shows how processes of literature search and review are likely to be affected by widespread and systematic biases.
Polonioli, Andrea
core  

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Res Synth Methods [PDF]

Systematic reviews are an essential tool for researchers, prevention providers and policy makers who want to remain current with the evidence in the field.

core