Results 231 to 240 of about 2,543,955 (363)

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Barriers and facilitators of domain-specific physical activity: a systematic review of reviews. [PDF]

BMC Public Health, 2022
Garcia L, Mendonça G, Benedetti TRB, Borges LJ, Streit IA, Christofoletti M, Silva-Júnior FLE, Papini CB, Binotto MA.   +8 more
europepmc   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Evaluating the evidence: a systematic review of reviews of the effectiveness and safety of digital interventions for ADHD. [PDF]

BMC Psychiatry
Gabarron E, Denecke K, Lopez-Campos G.
europepmc   +1 more source

Identification of outcomes reported for hospital antimicrobial stewardship interventions using a systematic review of reviews. [PDF]

JAC Antimicrob Resist, 2023
Yousuf S, Rzewuska M, Duncan E, Ramsay C.   +3 more
europepmc   +1 more source

Enterprise Resource Planning System Implementation Influence on Firms’ Performance: A Systematic Review

Saifullah Mohammadi, Arafat Mohammed, Hamza Hassa Abdirahman   +2 more
openalex   +2 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Interventions Addressing Health Literacy in Cancer Care: A Systematic Review of Reviews. [PDF]

Int J Environ Res Public Health
Jeitani C, Van den Broucke S, Leemans C.
europepmc   +1 more source

Allostatic Load Measurement: A Systematic Review of Reviews, Database Inventory, and Considerations for Neighborhood Research. [PDF]

Int J Environ Res Public Health, 2022
Beese S, Postma J, Graves JM.
europepmc   +1 more source

Annual Review of Ecology, Evolution, and Systematics, Volume 54

Barney Lipscomb
openalex   +2 more sources