Results 31 to 40 of about 552,583 (264)

The quality of COVID-19 systematic reviews during the coronavirus 2019 pandemic: an exploratory comparison

Systematic Reviews
Background The unprecedented volume and speed at which COVID-19-related systematic reviews (SRs) may have been produced has raised questions regarding the quality of this evidence.
Kevin T. McDermott, Mark Perry, Willemijn Linden, Rachel Croft, Robert Wolff, Jos Kleijnen   +5 more
doaj   +1 more source

Digital Biomarker–Based Interventions: Systematic Review of Systematic Reviews

Journal of Medical Internet Research, 2022
Background The introduction of new medical technologies such as sensors has accelerated the process of collecting patient data for relevant clinical decisions, which has led to the introduction of a new technology known as digital biomarkers.
Hossein Motahari-Nezhad, Hana Al-Abdulkarim, Meriem Fgaier, Mohamed Mahdi Abid, Márta Péntek, László Gulácsi, Zsombor Zrubka   +6 more
openaire   +3 more sources

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Accuracy and clinical effectiveness of fetal growth monitoring strategies for the prediction of small for gestational age at birth: a systematic review and meta-analysis

Health Technology Assessment
Background Smallness for gestational age has been associated with an increased risk of neonatal/fetal adverse outcomes. The Healthcare Safety Investigation Branch has issued a safety recommendation aimed at improving fetal growth monitoring strategies ...
Evangelos Danopoulos, Nigel Armstrong, Kevin McDermott, Jiongyu Chen, Xiaoyu Tian, Caro Noake, Marie Westwood   +6 more
doaj   +1 more source

A systematic review of systematic reviews of homeopathy [PDF]

British Journal of Clinical Pharmacology, 2002
Homeopathy remains one of the most controversial subjects in therapeutics. This article is an attempt to clarify its effectiveness based on recent systematic reviews. Electronic databases were searched for systematic reviews/meta‐analysis on the subject. Seventeen articles fulfilled the inclusion/exclusion criteria.
openaire   +2 more sources

Automation of systematic literature reviews: A systematic literature review

Information and Software Technology, 2021
Abstract Context Systematic Literature Review (SLR) studies aim to identify relevant primary papers, extract the required data, analyze, and synthesize results to gain further and broader insight into the investigated domain. Multiple SLR studies have been conducted in several domains, such as software engineering, medicine, and pharmacy. Conducting
van Dinter, Raymon, Tekinerdogan, Bedir, Catal, Cagatay   +2 more
openaire   +4 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

ImmunoCAP® ISAC and Microtest for multiplex allergen testing in people with difficult to manage allergic disease: a systematic review and cost analysis

Health Technology Assessment, 2016
Background: Allergy is a form of immune-mediated exaggerated sensitivity (hypersensitivity) to a substance that is either inhaled, swallowed, injected or comes into contact with the skin. Foreign substances that provoke allergies are called allergens. It
Marie Westwood, Bram Ramaekers, Shona Lang, Nigel Armstrong, Caro Noake, Shelley de Kock, Manuela Joore, Johan Severens, Jos Kleijnen   +8 more
doaj   +1 more source

Faecal immunochemical tests (FIT) can help to rule out colorectal cancer in patients presenting in primary care with lower abdominal symptoms: a systematic review conducted to inform new NICE DG30 diagnostic guidance

BMC Medicine, 2017
Background This study has attempted to assess the effectiveness of quantitative faecal immunochemical tests (FIT) for triage of people presenting with lower abdominal symptoms, where a referral to secondary care for investigation of suspected colorectal ...
Marie Westwood, Shona Lang, Nigel Armstrong, Sietze van Turenhout, Joaquín Cubiella, Lisa Stirk, Isaac Corro Ramos, Marianne Luyendijk, Remziye Zaim, Jos Kleijnen, Callum G. Fraser   +10 more
doaj   +1 more source

Role and utility of COVID-19 laboratory testing in low-income and middle-income countries: protocol for rapid evidence synthesis

BMJ Open, 2021
Introduction Accurate and affordable laboratory testing is key to timely diagnosis and appropriate management of patients with COVID-19. New laboratory test protocols are released into the market under emergency use authorisation with limited evidence on
Daniel Semakula, Eve Namisango, Nelson Sewankambo, Fred Nalugoda, Ojiambo Kevin Ouma, Kisangala Ephraim, Nakalembe Loyce, Regina Ndagire, Rachel Nante Wangi, Brenda Allen Kawala, Thomas Katairo, Allen Eva Okullo, Robert Apunyo, Ash Luwambo, Alison Annet Kinengyere, Sheila N Balinda, Moses Ocan, Ekwaro A Obuku   +17 more
doaj   +1 more source