Results 131 to 140 of about 1,783,022 (384)

Measurement error in medical research: a systematic review of current practice Senior Researcher

, 2018
In medical research, covariates (e.g. exposure and confounder variables) are often measured with error. While it is well accepted that this introduces bias and imprecision in exposure-outcome relations, it is unclear to what extent such issues are currently considered in research practice. The objective was to study common practices regarding covariate
Timo Brakenhoff, Marian Mitroiu, Ruth H Keogh, Karel GM Moons, Rolf H.H. Groenwold, Maarten van Smeden   +5 more
openaire   +3 more sources

Evaluation of methodological quality of studies

Senses and Sciences, 2016
Evidence-Based Medicine (EBM) is a systematic approach to medical question, integrating individual clinical expertise with the best available clinical evidence from systematic research.
Vanessa Palmeri, Vittoria Colamesta, Giuseppe La Torre   +2 more
doaj   +1 more source

A High‐Sensitivity Circulating Nucleic Acid Sequencing Assay for Assessing Treatment Response to Alectinib in a Pediatric Patient With ALK‐Rearranged Non–Small Cell Lung Cancer

Pediatric Blood &Cancer, EarlyView.
Alberto D. Guerra, Nicholas F. Evageliou, Vandana Batra, Kristen L. Dalton, Stephanie Ortel, Usman Ashraf, Tricia R. Bhatti, Lisa J. States, Lea F. Surrey, Theodore W. Laetsch   +9 more
wiley   +1 more source

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi, Daisuke Katagiri, Takeyuki Watadani, Shunichi Matsuda, Hiroshi Kaneko, Noritoshi Arai   +5 more
wiley   +1 more source

MOESM9 of Crowdsourcing in health and medical research: a systematic review

, 2020
Additional file 9: Table S15. Bias assessment of RCT studies exploring out-of-hospital CPR.
Wang, Cheng, Han, Larry, Stein, Gabriella, Day, Suzanne, Bien-Gund, Cedric, Mathews, Allison, Ong, Jason, Zhao, Pei-Zhen, Wei, Shu-Fang, Walker, Jennifer, Chou, Roger, Lee, Amy, Chen, Angela, Bayus, Barry, Tucker, Joseph   +14 more
openaire   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Online tools supporting the conduct and reporting of systematic reviews and systematic maps: a case study on CADIMA and review of existing tools

Environmental Evidence, 2018
Systematic reviews and systematic maps represent powerful tools to identify, collect, evaluate and summarise primary research pertinent to a specific research question or topic in a highly standardised and reproducible manner.
Christian Kohl, Emma J. McIntosh, Stefan Unger, Neal R. Haddaway, Steffen Kecke, Joachim Schiemann, Ralf Wilhelm   +6 more
doaj   +1 more source

NHMRC draft information paper: evidence on the effectiveness of homeopathy for treating health conditions [PDF]

This report summarises an assessment of homeopathy undertaken by the National Health and Medical Research Council, including an overview of published systematic reviews, evaluation of information provided by interest groups and the public, and ...

core  

What kind of systematic review should I conduct? A proposed typology and guidance for systematic reviewers in the medical and health sciences

BMC Medical Research Methodology, 2018
BackgroundSystematic reviews have been considered as the pillar on which evidence-based healthcare rests. Systematic review methodology has evolved and been modified over the years to accommodate the range of questions that may arise in the health and ...
Z. Munn, Cindy Stern, E. Aromataris, C. Lockwood, Z. Jordan   +4 more
semanticscholar   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source