Results 271 to 280 of about 1,783,022 (384)

Molecular cancer prevention: Intercepting disease

Molecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source

Research Waste, Redundancy and the Rise of the Machines: The Questionable Future of Systematic Reviews. [PDF]

Drug Alcohol Rev
Larney S.
europepmc   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Interventions for improving home food environments and household food security in adult populations residing in low-income settings: a systematic review protocol. [PDF]

BMJ Open
Madlala SS, Mabhida SE, Hill J.
europepmc   +1 more source

Erratum to: What incentives increase data sharing in health and medical research? A systematic review [PDF]

, 2017
Anisa Rowhani-Farid, Michelle Allen, Adrian Barnett   +2 more
openalex   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Alzheimer's Disease in Africa: A Scoping Review Protocol. [PDF]

Health Sci Rep
Nuamah JA, Avorgbedor FK, Dadson SS, Adu Asamoah E, Benson PY, Kukuia KKE, Kanmounye US.   +6 more
europepmc   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Factors Associated With Evolution of the Use of Medical Assistance in Dying: Protocol for a Scoping Review.

JMIR Res Protoc
Marcoux I, Lavoie D, Bergeron A, Beaudin A, Lemyre S, Bourgeois-Guérin V, Bravo G, Hébert M, Simard C, Ummel D, Perron C, Bouthillier ME.   +11 more
europepmc   +1 more source

Operationalizing and Measuring Informed Choice in Health Care: An Umbrella Review. [PDF]

Med Decis Making
Sprosen H, Re C, Stewart GD, Usher-Smith JA.   +3 more
europepmc   +1 more source