Results 121 to 130 of about 11,519,005 (304)

Improving Risk Assessment in Clinical Trials: Toward a Systematic Risk-Based Monitoring Approach. [PDF]

Curr Ther Res Clin Exp, 2021
Fneish F, Schaarschmidt F, Fortwengel G.
europepmc   +1 more source

Asset and systematic risk

African Journal of Business Management, 2012
In financial accounting, assets are economic resources. Anything tangible or intangible that is capable of being owned or controlled to produce value and that is held to have positive economic value is considered an asset. Simply stated, assets represent ownership of value that can be converted into cash (although cash itself is also considered an ...
openaire   +2 more sources

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Investigation and Systematic Risk Assessment in a Typical Contaminated Site of Hazardous Waste Treatment and Disposal. [PDF]

Front Public Health, 2021
Zhu W, Yang X, He J, Wang X, Lu R, Zhang Z.   +5 more
europepmc   +1 more source

Chapter 7: Systematic Reviews of Etiology and Risk

JBI Manual for Evidence Synthesis, 2020
Sandeep Moola, Z. Munn, C. Tufanaru, E. Aromataris, K. Sears, Raluca Sfetc, Maria Currie, K. Lisy, R. Qureshi, Patrick Mattis, P. Mu   +10 more
semanticscholar   +1 more source

Estimating systematic risk for the best investment decisions on manufacturing company in Indonesia

, 2017
Estimation of systematic risk is one of the important aspects of the best investment decisions. Through systematic risk prediction will be known risks to be faced by investors, because systematic risk is a measure of investment risk.
Zarah Puspitaningtyas
semanticscholar   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Performance of Arbitrage Mutual Funds: Risk, Fund Size and Market Sentiments – Evidence from India

American Business Review
We examine the theory of decreasing returns to scale by assessing the impact of fund size on the performance of arbitrage mutual funds in India. Fund manager of arbitrage funds with large fund size tend to hold cash equivalents due to inadequate ...
DMV Lakshmi Velagala, Satish Kumar, Kali Charan Sabat   +2 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Risk-based screening programmes for cancer diagnosis: A systematic review with narrative synthesis

Annals, Academy of Medicine, Singapore
Introduction: Risk-based screening (RBS) has emerged as a promising alternative to age-based cancer screening. However, evidence regarding real-world implementation outcomes remains fragmented.
Yong Yi Tan, Sara Tasnim, Mohammad Fahmy Bin Fadzil, Xin Rong Ng, Sabrina KW Wong, Jo-Anne Elizabeth Manski-Nankervis, Joseph Jao-Yiu Sung, Joanne Ngeow   +7 more
doaj   +1 more source