Results 91 to 100 of about 3,708,184 (376)

Quantization (Systematic) [PDF]

open access: yes, 2009
Contains fulltext : 75968.pdf (Publisher’s version ) (Open Access)
openaire   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Historical faunal exchange between the Pontocaspian Basin and North America

open access: yesEcology and Evolution, 2019
Ecrobia is a genus of small brackish‐water mud snails with an amphi‐Atlantic distribution. Interestingly, the species occurring in the northwestern Atlantic, Ecrobia truncata, is more closely related to the Pontocaspian taxa, Ecrobia grimmi and Ecrobia ...
Justine Vandendorpe   +5 more
doaj   +1 more source

Mitochondrial DNA discriminates distinct population of two deadly snakes (Reptilia: Elapidae) in Northeast India

open access: yesMitochondrial DNA. Part B. Resources, 2020
The DNA data of Indian snakes are scanty in the global database, especially from the northeastern states. The present study generated the mitochondrial Cytochrome b gene information of two morphologically identified deadly elapid species from Mizoram ...
Shantanu Kundu   +5 more
doaj   +1 more source

Using CMB lensing to constrain the multiplicative bias of cosmic shear

open access: yes, 2011
Weak gravitational lensing is one of the key probes of cosmology. Cosmic shear surveys aimed at measuring the distribution of matter in the universe are currently being carried out (Pan-STARRS) or planned for the coming decade (DES, LSST, EUCLID, WFIRST).
Alberto Vallinotto   +7 more
core   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Morphologic, Morphometric and Molecular Comparison of Two Sister Species of Rodents as Potential Reservoir Hosts of Zoonotic Cutaneous Leishmaniasis in the Southwest of Iran

open access: yesJournal of Medical Microbiology and Infectious Diseases, 2019
Introduction: Rodents are reservoir hosts of various infectious diseases. Many species and subspecies of genus Rattus play a significant role as potential reservoir hosts of different emerging and re-emerging diseases, including leishmaniasis.
Seyedeh Maryam Ghafari   +5 more
doaj  

Convergent evolution of specialized generalists: Implications for phylogenetic and functional diversity of carabid feeding groups

open access: yesEcology and Evolution, 2020
Closely related species are often assumed to be functionally similar. Phylogenetic information is thus widely used to infer functional diversity and assembly of communities.
Dennis Baulechner   +3 more
doaj   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

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