Results 121 to 130 of about 2,052,932 (306)

On decomposing net final values: EVA, SVA, and shadow project [PDF]

open access: yes
A residual-income model, named Systemic Value Added (SVA), is proposed for decision-making purposes, based on a systemic approach introduced in Magni (2000, 2003, 2004).
Magni, Carlo Alberto
core   +1 more source

A critical evaluation of the writing methods of selected scholars of African culture and traditional religion – E. B. Idowu; E. G. Parrinder and K. A. Opoku [PDF]

open access: yes, 2019
Every activity of man is often done in a certain way. This includes the study of religion. Scholars have generally adopted various methods in studying religion. Some of these methods have been classified as unacademic, while some are
Asuquo, Offiong Offiong
core  

Consciousness—a system-theoretical approach [PDF]

open access: yesFrontiers in Psychology, 2014
The aim of this work is not to compete with the paper by Boly et al. (2013), but rather to look at the issue of consciousness from a different, system-theoretical perspective. According to advice by Sokal and Bricmont that “it’s a good idea to know, what one is talking about” (Sokal and Bricmont, 1999, p.
openaire   +3 more sources

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

open access: yesFEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz   +9 more
wiley   +1 more source

Human-centricity in AI governance: A systemic approach. [PDF]

open access: yesFront Artif Intell, 2023
Sigfrids A   +3 more
europepmc   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

Organized crime requires dynamic decision making

open access: yesFrontiers in Psychology
It is extremely hard to successfully fight organized crime, not only because there are ambiguous and complex interactions between factors and actors, but also because organized crime is volatile and adaptive to changing conditions. This paper argues that,
José Kerstholt   +4 more
doaj   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

open access: yesFEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen   +6 more
wiley   +1 more source

A Systemic Approach to Innovation [PDF]

open access: yes, 2001
The objective of this paper is to increase our ability to understand the systems of innovation approach as a flexible and useful conceptual framework for innovation analysis.
Fischer, Manfred M.
core  

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