Results 121 to 130 of about 12,519,817 (288)
FEBS Open Bio, EarlyView.The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez +4 more
wiley +1 more source
Development and Application of an Integrated Index for Occupational Safety Evaluation
SafetyOccupational safety, reflecting the likelihood of work-related accidents, is crucial in work systems. A risk management model identifies, analyzes, and prioritizes risks, followed by the strategic application of resources to mitigate, monitor, and ...
Paulo Silva +6 more
doaj +1 more source
Cell surface CD11c as a neutrophil aging marker molecule
FEBS Open Bio, EarlyView.Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki +5 more
wiley +1 more source
Integrative Model of Human-Animal Interactions: A One Health-One Welfare Systemic Approach to Studying HAI. [PDF]
Front Vet Sci, 2022 Leconstant C, Spitz E.
europepmc +1 more source
FEBS Open Bio, EarlyView.This pilot study investigates the potential of Generative AI to provide formative feedback to students. ChatGPT was prompted to provide feedback on Year 1 Bioscience essays, which were evaluated against established good feedback practices. GenAI‐authored feedback had useful elements, but was limited in scope. GenAI may have potential to provide instant,
Annabel Court +3 more
wiley +1 more source
Perspectives Interdisciplinaires sur le Travail et la SantéThe double regulation model, also known as the five-square model proposed by Leplat and Cuny in 1977, remains central to activity analysis in ergonomics as it constitutes an open framework and a matrix for understanding activity in real-world situations.
Muriel Prévot-Carpentier, Cathy Toupin
doaj +1 more source
Storage Time as an Index for Varietal Prediction of Mango Ripening: A Systemic Approach Validated on Five Senegalese Varieties. [PDF]
Foods, 2022 Dieye M +6 more
europepmc +1 more source
Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells
FEBS Open Bio, EarlyView.Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla +10 more
wiley +1 more source
Liaisons Dangereuses: Increasing Connectivity, Risk Sharing, and Systemic Risk [PDF]
We characterize the evolution over time of a network of credit relations among financial agents as a system of coupled stochastic processes. Each process describes the dynamics of individual financial robustness, while the coupling results from a network
Bruce C. Greenwald +4 more
core
The 'Covid-Trigger': New Light on Urban Agriculture and Systemic Approach to Urbanism to Co-Create a Sustainable Lisbon. [PDF]
Syst Pract Action Res, 2023 Simon S.
europepmc +1 more source