Results 101 to 110 of about 12,519,817 (288)

Structural Elements of Criminal Policy

Сибирское юридическое обозрение
The subject of this study is criminal policy as a complex system of public administration in the sphere of countering crime. The aim of the article is to provide a systemic analysis of its structural elements, to identify their interrelations and ...
D. A. Novokshonov
doaj   +1 more source

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

Molecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

Ending the Document Game: Connecting and Transforming Your Healthcare Through Information Technlogy

, 2005
The Commission on Systemic Interoperability was authorized by the Medicare Modernization Act and established by the Secretary of Health and Human Services. Its members were appointed by the President of the United States of America and the leaders of the
Commission on Systemic Interoperability
core  

Prevalence of social risk factors and its trends in the population of women of reproductive age at the territorial level

Якутский медицинский журнал
Introduction. Tumours affecting the reproductive organs are diagnosed in women of fertile age in 20–40% of cases. Therefore, the current situation not only affects the quality and life expectancy of patients, but also leads to a decrease in the ...
I. P. Aminodova, T. P. Vasilieva, S. V. Russkikh, L. N. Afanasyeva, M. D. Vasiliev   +4 more
doaj   +1 more source

Human-centricity in AI governance: A systemic approach. [PDF]

Front Artif Intell, 2023
Sigfrids A, Leikas J, Salo-Pöntinen H, Koskimies E.   +3 more
europepmc   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

A framework for assessing systemic risk [PDF]

When faced with financial crises, authorities worldwide tend to respond aggressively with public support measures. Given the adverse impact on moral hazard and market discipline, support measures involving public money are ideally limited to crisis ...
Dijkman, Miquel
core  

A Systemic Approach to Innovation

, 2002
The context of this chapter is set by the contemporary transition from an industrial to a knowledge-based economy. OECD (1996a) has documented the way in which the knowledge-based economy of learning individuals, organisations and economies is emerging out of the machine-based economy that determined advanced economies in most of the time in the 20th ...
openaire   +3 more sources

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source