Results 101 to 110 of about 6,373,239 (386)
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
The Emergence of Symbol-Based Communication in a Complex System of Artificial Creatures [PDF]
, 2005 We present here a digital scenario to simulate the emergence of self-organized symbol-based communication among artificial creatures inhabiting a virtual world of predatory events. In order to design the environment and creatures, we seek theoretical and
El-Hani, Charbel +3 more
core +1 more source
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
Molecular Oncology, EarlyView.p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
Migraine In Systemic Lupus Erythematosus in Rheumatological outpatients unit
مجله كليه طب الكندي, 2019 Background: Migraine is common in systemic lupus erythematosus.It is a significant source of patient disability. Objective: To determine the rate of migraine in patients with systemic lupus erythematosus, to assess migraine type, severity, and the ...
Ameer Shaker
doaj +1 more source
Blood-based bioenergetic profiling is related to differences in brain morphology in African Americans with Type 2 diabetes. [PDF]
, 2018 Blood-based bioenergetic profiling has promising applications as a minimally invasive biomarker of systemic bioenergetic capacity. In the present study, we examined peripheral blood mononuclear cell (PBMC) mitochondrial function and brain morphology in a
Freedman, Barry I +6 more
core
MASLD: a systemic metabolic disorder with cardiovascular and malignant complications
GutNon-alcoholic fatty liver disease (NAFLD) has rapidly become the most common chronic liver disease globally and is currently estimated to affect up to 38% of the global adult population.
G. Targher +2 more
semanticscholar +1 more source
Associations between diabetic retinopathy and systemic risk factors.
Hong Kong medical journal = Xianggang yi xue za zhi, 2016 INTRODUCTION Diabetes mellitus is a systemic disease with complications that include sight-threatening diabetic retinopathy. It is essential to understand the risk factors of diabetic retinopathy before effective prevention can be implemented. The aim of
Noel Wat, R. Wong, Ian YH Wong
semanticscholar +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Dilated superior ophthalmic vein: systemic associations. [PDF]
Int Ophthalmol, 2023 Rana K +4 more
europepmc +1 more source
Associative systems of left quotients
Journal of Algebra, 2005 Taking as starting point the idea that the study of maximal quotient systems (the analogues of the maximal quotient ring) for associative pairs and triple systems could shed light on the structure theory of Jordan systems (algebras, pairs or triples) and of Lie algebras, the authors develop a theory for these quotient systems.
Aranda Pino, Gonzalo +1 more
openaire +1 more source