Results 81 to 90 of about 349,014 (261)

Associations between systemic immune-inflammation index and iron deficiency

Scientific Reports
The systemic immune-inflammation index (SII) is widely used in monitoring disease progression, evaluating treatment efficacy, and predicting outcomes across diverse diseases. Yet, its roles in iron deficiency (ID) remains unclear. This investigation aims
Peiyun Guo, Rui Kang, Xin Zhao
doaj   +1 more source

Systemic Drugs Associated With Maculopathy

JAMA Ophthalmology
Importance Systemic medications may have unrecognized macular toxic effects; early identification might be important for vision preservation. Objectives To identify systemic drugs potentially associated with maculopathy via ...
Kim, Jiyeong, Ahn, Seong Joon, Park, Jiyeon, Gower, Emily W., Chung, Jee-Eun   +4 more
openaire   +2 more sources

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Association between systemic immune-inflammation index and urinary incontinence: Evidence from the National Health and Nutrition Examination Survey

Journal of International Medical Research
Objective This study examined the association between the systemic immune-inflammation index and urinary incontinence subtypes using data from National Health and Nutrition Examination Survey 2007–2016.
Feike Ma, Zhi-Cheng Cong, Hao Zhang, Yi-Han Chen, Yi-Lun Cui, Yue Duan, Ting-Ting Tao   +6 more
doaj   +1 more source

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source

Periodontitis and systemic diseases: insights into the correlation, mechanisms, and clinical implications

Frontiers in Immunology
Periodontitis is a chronic oral infectious inflammatory disease caused by dental plaque, affecting approximately 35% - 50% of adults globally. Far from a localized oral condition, it exerts systemic pathogenic effects through multiple biological conduits.
Zhina Wu, Yaoyao Zhang, Lishan Wang, Yating Yi, Bingfeng Dai, Huanyun Chen, Fanghong Yang, Fanghong Yang   +7 more
doaj   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Associations between socioeconomic factors and mental symptoms highlight whole-body correlates and pathways

iScience
Summary: Socioeconomic status (SES) correlates with both mental symptoms and systemic health traits, suggesting systemic health conditions as potential complementary pathways for SES-mental health associations alongside neural mechanisms.
Guoshu Zhao, Jie Tang, Zehao Wang, Qian Qian, Shaoying Wang, Nannan Zhang, Jinghan Sun, Hui Xue, Zuhao Sun, Yingying Xie, Zirui Wang, Huaigui Liu, Hao Ding, Feng Liu, Wen Qin, Meng Liang, Jiayuan Xu, Chunshui Yu   +17 more
doaj   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source