Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Longitudinal Relationships of Subclinical Cardiovascular Disease with Physical Function in Older Adults [PDF]
, 2009 Low ankle-arm index (AAI), a marker of peripheral arterial disease, predicts incident disability in older adults. Elevated pulse wave velocity (PWV), a measure of arterial stiffness, increases risk of cardiovascular events and mortality.
Watson, Nora Lynn
core
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Associations between systemic inflammation and cognitive trajectories post-stroke
Scientific ReportsOur objective was to explore whether plasma inflammatory biomarkers and related metabolites in acute phase and 3 months after stroke were associated with different cognitive trajectories and with changes in cognition post-stroke.
Heidi Vihovde Sandvig +12 more
doaj +1 more source
Association of Expression of CD44v6 With Systemic Anaplastic Large Cell Lymphoma [PDF]
, 2002 Xiayuan Liang +6 more
openalex +1 more source
Association between Systemic Factors and Vitreous Fluid Cytokines in Proliferative Diabetic Retinopathy [PDF]
, 2023 Tomohito Sato +7 more
openalex +1 more source
Periodontitis and the Elderly: An Overview of the Disease and its Impact on an Aging Population [PDF]
, 2019 Periodontitis affects millions of Americans each year, and is especially prevalent among the elderly. Since periodontitis is a chronic, progressive condition, uninterrupted disease progression leads to irreversible oral damage; therefore, periodontitis ...
Weissenfluh, Nicole Grace
core +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Associations between systemic immune-inflammation index and iron deficiency
Scientific ReportsThe systemic immune-inflammation index (SII) is widely used in monitoring disease progression, evaluating treatment efficacy, and predicting outcomes across diverse diseases. Yet, its roles in iron deficiency (ID) remains unclear. This investigation aims
Peiyun Guo, Rui Kang, Xin Zhao
doaj +1 more source
Association Between Antinuclear Antibodies and interstitial lung Diseases in patients with Systemic Lupus Erythematosus [PDF]
, 2019 Walaa Hamed +2 more
openalex +1 more source