Results 71 to 80 of about 15,163,780 (323)

Transition product design. A framework proposal for a holistic approach to systemic design

Agathón, 2022
The Transition Design (TD) discipline is based on a design framework and methodology that prioritises social and environmental well-being and the goals of local resilience and radical changes in socio-technical contexts.
Mario Bisson, Stefania Palmieri, Alessandro Ianniello, Luca Botta   +3 more
doaj   +1 more source

Accessibility of Tourism Space from a Geographical Perspective [PDF]

, 2014
The accessibility of tourism space is becoming an increasingly significant issue in geographical research due to, amongst other things, demographic changes (an ageing population, growing numbers of people with disabilities) alongside guaranteeing a ...
Zajadacz, Alina
core   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Exploring systemic design practices in public sector innovation

Policy Design and Practice
Many societal challenges need to be resolved through innovative solutions at system level. Previous scholars have argued that it may be wise to combine design practice and system theory to form a management method for public sector innovation.
Klas Palm, Svea Fredriksson, Elin Silfversten, Nurgül Özbek   +3 more
doaj   +1 more source

Systemic Design for Sustainable Healthcare

, 2017
The healthcare sector is a complex system that is facing new emerging trends without, however, having the proper resources and structures to address them.
S. Barbero, Agnese Pallaro
semanticscholar   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Integrated Wearable System for Monitoring Skeletal Muscle Force of Lower Extremities

Sensors
Continuous monitoring of lower extremity muscles is necessary, as the muscles support many human daily activities, such as maintaining balance, standing, walking, running, and jumping.
Heng Luo, Ying Xiong, Mingyue Zhu, Xijun Wei, Xiaoming Tao   +4 more
doaj   +1 more source

Modelagem sistêmica e simulação: estratégia de gestão no Processo de Projeto para a Experiência do Usuário (UXD)

Gestão & Produção, 2017
Resumo A coleta, análise e avaliação de dados heterogêneos, provenientes da interação de usuários, com as mais diferentes tecnologias e soluções propostas, são de suma importância para o Processo de Projeto para a Experiência do Usuário (UXD). Entretanto,
Cristiane Ellwanger, Régio Pierre da Silva, Rudimar Antunes da Rocha   +2 more
doaj   +1 more source

Codifying systemic design: A toolkit [PDF]

, 2016
In this paper we want to reflect on the use of toolkits as a codification strategy to fuel an expanding practice of ‘systemic design’. This critical reflection is rooted in the real‐life experience of bringing together two different sets of skills in ...
Bertels, Peter, Thoelen, Annelies, Van Ael, Kristel, Vandenbroeck, Philippe   +3 more
core   +1 more source