Results 81 to 90 of about 15,163,780 (323)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

The EQUAL model for equity: A systems-based design to prevent school dropout in Thailand

open access: yesInternational Journal of Educational Research Open
This study examined the multifaceted factors influencing school dropout among vulnerable children in Thailand and analyzed mechanisms of Thailand Zero Dropout (TZD) policy implementation.
Kittipong Pearnpitak
doaj   +1 more source

Relating Systems Thinking and Design I. Practical Advances in Systemic Design

open access: yesFORMakademisk, 2014
This issue, Relating Systems Thinking and Design I – Practical Advances in Systemic Design, along with Issue 7:4, Relating Systems Thinking II – Theoretical Evolution in Systemic Design, together form a double special issue of FORMakademisk on the theory
Birger Sevaldson, Alex J. Ryan
doaj   +1 more source

Systemic Design, from the content to the structure of education: new educational model.

open access: yes, 2017
In the 19th century, new discoveries permitted to pass from the Cartesian mechanism to a holistic view of life. In the educational field movements as Constructivist Learning and Holistic Education have represented an important contribution to this change
Chiara Battistoni, S. Barbero
semanticscholar   +1 more source

The New White Flight [PDF]

open access: yes, 2014
White charter school enclaves—defined as charter schools located in school districts that are thirty percent or less white, but that enroll a student body that is fifty percent or greater white— are emerging across the country.
A. R. Karimov   +10 more
core   +3 more sources

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

open access: yesMolecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad   +35 more
wiley   +1 more source

Gigamaps as enabling tools for envisioning futures

open access: yesAkademisk Kvarter, 2023
Entrepreneurial ecosystems have gained attention for fostering innovation and sustainable transition. However, their complexity poses challenges, especially when different companies co-design for future making toward sustainable transition strategies ...
Cecilia Padula, Silvia Barbero
doaj  

Relating Systems Thinking & Design 2013. Emerging Contexts for Systemic Design

open access: yesFORMakademisk, 2013
AHO – Oslo School of Architecture & Design, Norway, invites to the Relating Systems Thinking and Design to a free and open symposium over two days 9th-11th October 2013, with a preceding full day with diverse workshops and a subsequent special issue in ...
Birger Sevaldson
doaj   +1 more source

Banking Concentration: Implications for Systemic Risk and Safety Net Design [PDF]

open access: yes
This paper explores the impact of banking concentration on safety net design –in particular, deposit insurance– and on systemic risk. The paper focuses on a system characterized by high concentration and low total number of banks. Each issue is addressed
Rodrigo Cifuentes
core   +3 more sources

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

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