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Dry eye and systemic diseases [PDF]

open access: yesSaudi J Ophthalmol
Tear film instability and reduced tear production initiate a vicious circle where hyperosmolarity, ocular inflammation, and apoptosis may induce a damage of the ocular surface including keratitis which is all included in a common condition called dry eye
Iaccarino, Luca   +3 more
core   +2 more sources

Effects of Antiseptic Formulations on Oral Microbiota and Related Systemic Diseases: A Scoping Review [PDF]

open access: yesAntibiotics (Basel)
Background: Oral antiseptic formulations are widely used as adjuncts in oral hygiene to reduce pathogenic microorganisms and prevent oral diseases.
Elena Jovanova   +4 more
core   +2 more sources

Endothelial Progenitor Cells: Relevant Players in the Vasculopathy and Lung Fibrosis Associated with the Presence of Interstitial Lung Disease in Systemic Sclerosis Patients

open access: yesBiomedicines, 2021
Endothelial progenitor cells (EPC), which are key effectors in the physiologic vascular network, have been described as relevant players in autoimmune diseases.
Verónica Pulito-Cueto   +15 more
doaj   +1 more source

Thrombosis and Hyperinflammation in COVID-19 Acute Phase Are Related to Anti-Phosphatidylserine and Anti-Phosphatidylinositol Antibody Positivity

open access: yesBiomedicines, 2023
Antiphospholipid antibodies (APLA) are strongly associated with thrombosis seen in patients with antiphospholipid syndrome. In COVID-19, thrombosis has been observed as one of the main comorbidities.
Jaume Alijotas-Reig   +5 more
doaj   +1 more source

Angiogenic T Cells: Potential Biomarkers for the Early Diagnosis of Interstitial Lung Disease in Autoimmune Diseases?

open access: yesBiomedicines, 2022
(1) Background: We explored, for the first time, the contribution of angiogenic T cells (TAng) in interstitial lung disease associated to autoimmune disease (AD-ILD+) as potential biomarkers of the disease, evaluating their role in the underlying ...
Verónica Pulito-Cueto   +15 more
doaj   +1 more source

Disease activity influences the reclassification of rheumatoid arthritis into very high cardiovascular risk

open access: yesArthritis Research & Therapy, 2021
Background Previous studies have shown that risk chart algorithms, such as the Systematic Coronary Risk Assessment (SCORE), often underestimate the actual cardiovascular (CV) risk of patients with rheumatoid arthritis (RA).
Iván Ferraz-Amaro   +7 more
doaj   +1 more source

Neutrophil-Derived IL-6 Potentially Drives Ferroptosis Resistance in B Cells in Lupus Kidney

open access: yesMediators of Inflammation, 2023
Ferroptosis resistance is vital for B cell development, especially in inflammatory diseases, yet the underlying mechanism is still unclear. In this study, based on the scRNA-seq technique and flow cytometry, we discovered a proportion of neutrophils ...
Zechen Wang   +9 more
doaj   +1 more source

Ocular manifestations of systemic diseases in children

open access: yes, 2023
Knowledge of ocular diseases and understanding of the complex interplay between eye and systemic health have increased over the years. This knowledge is particularly important when caring for our youngest and most vulnerable paediatric patients when ...
Chong, Cheefoong   +2 more
core   +1 more source

Role of VEGF Polymorphisms in the Susceptibility and Severity of Interstitial Lung Disease

open access: yesBiomedicines, 2021
The search for biomarkers that can help to establish an early diagnosis and prognosis of interstitial lung disease (ILD) is of potential interest. VEGF polymorphisms have been implicated in the development of several lung disorders.
Sara Remuzgo-Martínez   +18 more
doaj   +1 more source

The significance of prolactin in systemic connective tissue diseases

open access: yes, 2023
Objectives Does prolactin (PRL) level testing in the diagnosis of systemic connective tissue diseases make sense and should we test it in everyday practice?
Michał Piotr Jakubaszek
core   +1 more source

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