Results 11 to 20 of about 1,311,352 (316)
Life, 2023 Glaucoma is the leading cause of irreversible blindness in the world. Due to its potential to cause permanent vision loss, it is important to understand how systemic conditions and their respective treatments can be associated with or increase the risk for developing glaucoma.
Eugene Hsu, Manishi Desai
openaire +3 more sources
Orphanet Journal of Rare Diseases, 2019 Background Rare disease diagnosis is often delayed by years. A primary factor for this delay is a lack of knowledge and awareness regarding rare diseases.
Simon Ronicke +5 more
doaj +1 more source
Serum cytokines to predict systemic lupus erythematosus clinical and serological activity
Clinical and Translational Science, 2022 We aimed to explore the role of interleukin (IL)‐6, interferon‐gamma (IFNγ), IL‐10, and tumor necrosis factor (TNF) as predictors of systemic lupus erythematosus (SLE) clinical and serological activity, and their correlation with the treatment received ...
Victor Moreno‐Torres +9 more
doaj +1 more source
Systemic diseases and the cornea [PDF]
, 2021 There is a number of systemic diseases affecting the cornea. These include endocrine disorders (diabetes, Graves' disease, Addison's disease, hyperparathyroidism), infections with viruses (SARS-CoV-2, herpes simplex, varicella zoster, HTLV-1, Epstein ...
Kramerov, Andrei A +8 more
core +1 more source
Impact of severe infections in SLE: an observational study from the Spanish national registry
Lupus Science and Medicine, 2022 Objective Infections are a common complication of SLE. Our objective was to evaluate their causes and impact on the survival of patients with SLE.Methods Analysis of the admissions and death causes in patients diagnosed with SLE from the Spanish Hospital
Guillermo Ruiz-Irastorza +11 more
doaj +1 more source
Role of MUC1 rs4072037 polymorphism and serum KL-6 levels in patients with antisynthetase syndrome
Scientific Reports, 2021 Mucin 1/Krebs von den Lungen-6 (KL-6) is proposed as a serum biomarker of several interstitial lung diseases (ILDs), including connective tissue disorders associated with ILD. However, it has not been studied in a large cohort of Caucasian antisynthetase
Sara Remuzgo-Martínez +30 more
doaj +1 more source
Frontiers in Immunology, 2021 Recent studies suggest that elevated CXCL13 serum levels in patients with primary Sjögren’s syndrome (pSS) associate with minor salivary gland (MSG) histologic features, disease severity, as well as high-risk status for non-Hodgkin lymphoma (NHL ...
Loukas Chatzis +11 more
doaj +1 more source
Childhood versus adulthood-onset autoinflammatory disorders: myths and truths intertwined
Reumatismo, 2013 Autoinflammatory disorders are characterized by spontaneous episodes of systemic inflammation deriving from inherited defects of the innate immune system.
L. Cantarini +9 more
doaj +1 more source
Arthritis Research & Therapy, 2018 Background To determine whether lung involvement is related to microvascular perturbations, nailfold videocapillaroscopy (NVC) was performed in patients with systemic sclerosis (SSc).
Alfredo Guillén-Del-Castillo +6 more
doaj +1 more source
Lack of the long pentraxin PTX3 promotes autoimmune lung disease but not glomerulonephritis in murine systemic lupus erythematosus. [PDF]
, 2011 The long pentraxin PTX3 has multiple roles in innate immunity. For example, PTX3 regulates C1q binding to pathogens and dead cells and regulates their uptake by phagocytes. It also inhibits P-selectin-mediated recruitment of leukocytes.
Mantovani Alberto +32 more
core +1 more source