Results 11 to 20 of about 1,901,654 (301)

Can a decision support system accelerate rare disease diagnosis? Evaluating the potential impact of Ada DX in a retrospective study

open access: yesOrphanet Journal of Rare Diseases, 2019
Background Rare disease diagnosis is often delayed by years. A primary factor for this delay is a lack of knowledge and awareness regarding rare diseases.
Simon Ronicke   +5 more
doaj   +1 more source

Serum cytokines to predict systemic lupus erythematosus clinical and serological activity

open access: yesClinical and Translational Science, 2022
We aimed to explore the role of interleukin (IL)‐6, interferon‐gamma (IFNγ), IL‐10, and tumor necrosis factor (TNF) as predictors of systemic lupus erythematosus (SLE) clinical and serological activity, and their correlation with the treatment received ...
Victor Moreno‐Torres   +9 more
doaj   +1 more source

Impact of severe infections in SLE: an observational study from the Spanish national registry

open access: yesLupus Science and Medicine, 2022
Objective Infections are a common complication of SLE. Our objective was to evaluate their causes and impact on the survival of patients with SLE.Methods Analysis of the admissions and death causes in patients diagnosed with SLE from the Spanish Hospital
Guillermo Ruiz-Irastorza   +11 more
doaj   +1 more source

Audio-vestibular symptoms in systemic autoimmune diseases [PDF]

open access: yes, 2018
Immune-mediated inner ear disease can be primary, when the autoimmune response is against the inner ear, or secondary. The latter is characterized by the involvement of the ear in the presence of systemic autoimmune conditions. Sensorineural hearing loss
Adelchi, Croce   +7 more
core   +1 more source

MyD88-dependent interplay between myeloid and endothelial cells in the initiation and progression of obesity-associated inflammatory diseases. [PDF]

open access: yes, 2014
Low-grade systemic inflammation is often associated with metabolic syndrome, which plays a critical role in the development of the obesity-associated inflammatory diseases, including insulin resistance and atherosclerosis.
DeFranco, Anthony L   +19 more
core   +2 more sources

Role of MUC1 rs4072037 polymorphism and serum KL-6 levels in patients with antisynthetase syndrome

open access: yesScientific Reports, 2021
Mucin 1/Krebs von den Lungen-6 (KL-6) is proposed as a serum biomarker of several interstitial lung diseases (ILDs), including connective tissue disorders associated with ILD. However, it has not been studied in a large cohort of Caucasian antisynthetase
Sara Remuzgo-Martínez   +30 more
doaj   +1 more source

Serum, but Not Saliva, CXCL13 Levels Associate With Infiltrating CXCL13+ Cells in the Minor Salivary Gland Lesions and Other Histologic Parameters in Patients With Sjögren’s Syndrome

open access: yesFrontiers in Immunology, 2021
Recent studies suggest that elevated CXCL13 serum levels in patients with primary Sjögren’s syndrome (pSS) associate with minor salivary gland (MSG) histologic features, disease severity, as well as high-risk status for non-Hodgkin lymphoma (NHL ...
Loukas Chatzis   +11 more
doaj   +1 more source

Non-systemic transmission of tick-borne diseases: a network approach [PDF]

open access: yes, 2016
Tick-Borne diseases can be transmitted via non-systemic (NS) transmission. This occurs when tick gets the infection by co-feeding with infected ticks on the same host resulting in a direct pathogen transmission between the vectors, without infecting the ...
Bajardi, Paolo   +2 more
core   +2 more sources

Antioxidant Supplementation in the Treatment of Aging-Associated Diseases [PDF]

open access: yes, 2016
Oxidative stress is generally considered as the consequence of an imbalance between pro- and antioxidants species, which often results into indiscriminate and global damage at the organismal level.
Conti, V   +7 more
core   +2 more sources

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