Results 41 to 50 of about 6,713,043 (291)

Relation Between Systemic Immune-Inflammation Index and Post PCI Bleeding Risk in STEMI Patients [PDF]

Objectives: To investigate the relationship between the systemic immune-inflammation index (SII) and bleeding complications in ST-elevated myocardial infarction (STEMI) after percutaneous coronary intervention (pPCI).
Çağatay Tunca, Ahmet Kıvrak, Murat Akdoğan, Ahmet Akdi, Kamuran Kalkan, Yunus Emre Özbebek, Onur Akgün, Hacı Ali Kürklü, Ayşenur Özkaya İbiş, Veysel Ozan Tanık, Akgün, Onur, Özkaya İbiş, Ayşenur, Kürklü, Hacı Ali, Tanık, Veysel Ozan, Kıvrak, Ahmet, Kalkan, KAMURAN, Tunca, Çağatay, Özbebek, Yunus Emre, Akdoğan, Murat, Akdi, Ahmet   +19 more
core   +1 more source

Systemic Immune-Inflammation Index May Predict Mortality in Neuroblastoma

Cureus, 2023
Neuroblastomas (NB) are among the most frequent childhood solid tumors. The link between inflammation and cancer is well understood. Many research studies have been conducted to determine the prognostic importance of inflammatory markers in cancer patients.
Cesur, Ilknur Banlı, Özçelik, Zerrin
openaire   +2 more sources

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

The systemic-immune-inflammation index predicts the recurrence of atrial fibrillation after cryomaze concomitant with mitral valve surgery

BMC Cardiovascular Disorders, 2022
Background and aims Inflammation plays a key role in the initiation and progression of atrial fibrillation (AF). The systemic inflammation indexes are easily evaluated and predict AF development.
Yu Luo, Jian Zhang, Tao Liu, Zongtao Yin, Yan Jin, Jinsong Han, Zhipeng Guo, Huishan Wang   +7 more
doaj   +1 more source

The role of systemic immune inflammation index in predicting melanoma

Frontiers in Oncology
Many malignancies arise in the context of chronic infection, persistent irritation, or unresolved inflammation, and the inflammatory environment is closely associated with tumor cell proliferation and metastatic spread. The systemic immune-inflammation index (SII), calculated from peripheral lymphocyte, neutrophil, and platelet counts, has been ...
Tao, Qingxiu, Wang, Chunli, Zeng, Long, Mao, Mengjie, Lu, Yingchun, Wang, Chunyu, Liu, Bin   +6 more
openaire   +3 more sources

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Systemic immune-inflammation index and systemic inflammation response index: novel hematological predictors of obstructive sleep apnea

Frontiers in Neurology
BackgroundWhile the association between obstructive sleep apnea (OSA) and chronic inflammation is well-established, the role of novel hematological indices, such as the systemic immune-inflammation index (SII) and systemic inflammation response index ...
Guohua He, Mingzhu Deng, Yangping Tong, Zhen Wan, Wei Xu, Tieqiao Feng, Wengao Zeng, Ling Xiao, Dandan Yang, Kangping Song, Fangyi Li   +10 more
doaj   +1 more source

Correlation of systemic immune-inflammation Index with surgical necrotizing enterocolitis

Frontiers in Pediatrics, 2022
BackgroundSystemic Immune-Inflammation Index (SII), known as an easy, economical and useful marker, correlates with the severity of inflammatory response. However, the usefulness of SII in necrotizing enterocolitis (NEC) remains unclear. Therefore, we evaluated the correlation of SII at NEC diagnosis and subsequent surgery.MethodsRetrospective review ...
Wei Feng, Jinping Hou, Chenzhu Xiang, Xiaohong Die, Jing Sun, Zhenhua Guo, Wei Liu, Yi Wang   +7 more
openaire   +3 more sources

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source