Results 71 to 80 of about 6,713,043 (291)

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Systemic Immune Inflammation Index in Ankylosing Spondylitis Patients

Türk Osteoporoz Dergisi
Objective: Our objective was to assess the relationship between disease activity and the systemic immune-inflammation index [SII; (platelet count × neutrophil count / lymphocyte count)] in individuals with ankylosing spondylitis (AS).
Salim Mısırcı, Alev Alp, Lale Altan, Büşra Başar Yılmaz   +3 more
doaj   +1 more source

The systemic immune-inflammation index and systemic inflammation response index are useful for predicting mortality in patients with diabetic nephropathy

Diabetology & Metabolic Syndrome
This study investigated the correlation between the systemic immune-inflammation index (SII) and the systemic inflammation response index (SIRI) and all-cause, cardiovascular, and kidney disease mortality in patients with diabetic nephropathy (DN). It aimed to provide a new predictive assessment tool for the clinic and a scientific basis for managing ...
Fan Zhang, Yan Han, Yonghua Mao, Wenjian Li   +3 more
openaire   +3 more sources

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

A retrospective observational study on the prognostic role of inflammatory markers in futile recanalization after endovascular treatment for large-vessel stroke

Journal of International Medical Research
Objective Endovascular treatment has proven to be effective in improving the outcome of patients with large-vessel stroke. However, more than half of the patients experience poor outcomes despite successful recanalization, which was defined as futile ...
Zubing Xu, Linghong Guo, Yunqing Chen, Dandan Chen, Hudie Zhang, Xilin Xiong, Yan Gong, Qiulong Yu, Chenying Zeng, Lanjiao Zhang, Qin Huang, Jinchong Zhang, Keji Zou, Pu Fang, Daojun Hong, Jing Lin, Xian Liu, Xiaobing Li   +17 more
doaj   +1 more source

THE SYSTEMIC-IMMUNE INFLAMMATION INDEX IN NATURALLY OBESE DOGS [PDF]

Assiut Veterinary Medical Journal
Obesity is one of the most prevalent health problems in the canine population. This study aimed to evaluate the clinical usability of the systemic immune inflammation index (SII) in obese dogs. A total of 25 obese dogs compared with 10 normal-weight dogs.
BÜLENT ULUTAŞ, GÜLTEN TUNA
doaj   +1 more source

High systemic immune–inflammation index represents an unfavorable prognosis of malignant pleural mesothelioma

, 2019
Ming Ma,1 Nina Yu,2 Bing Wu11Department of Radiation Oncology, Linyi People’s Hospital, Linyi, People’s Republic of China; 2Department of Gynecology and Obstetrics, Linyi People’s Hospital, Linyi, People’s Republic of ...
Yu N, Ma M, Wu B
core  

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Systemic immune-inflammation index and mortality among individuals with circadian syndrome

Journal of International Medical Research
Objective Evidence on the impact of the systemic immune-inflammation index on mortality risk among individuals with circadian syndrome is scarce. This study aimed to examine the association of the systemic immune-inflammation index with all-cause ...
Yunyan Lu, Tian Lan
doaj   +1 more source

Sedentary behavior is associated with systemic immune-inflammation index and systemic inflammation response index levels: a cross-sectional analysis of the NHANES 2011–2018

Frontiers in Public Health
BackgroundSedentary behavior (SB), has been closely linked to numerous detrimental health effects. While the individual and combined impacts of such behaviors on immune-inflammatory responses remain ambiguous, innovative indices like the Systemic Immune ...
Xian Wu, Lin Zhong, Yuehong Hu, Lingying Ruan, Kaiyu Zhou, Hanmin Liu, Lina Chen   +6 more
doaj   +1 more source