Results 81 to 90 of about 6,713,043 (291)

A novel predictor in patients with coronary chronic total occlusion: systemic immune-inflammation index: a single-center cross-sectional study

, 2022
OBJECTIVE: Severe inflammation is reportedly associated with subsequent cardiovascular events, including in patients with coronary artery disease. This study aimed to examine the prognostic value of systemic immune-inflammation index and determine ...
Demir, Muhammed, Özbek, Mehmet
core   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Relationship between Systemic Immune-inflammation Index and Mortality in Intensive Care Patients Diagnosed with Crimean-Congo Hemorrhagic Fever

, 2022
Objective: To evaluate the power of the systemic immune-inflammation index in the prediction of mortality in severe Crimean--Congo hemorrhagic fever patients. Study Design: Observational study. Place and Duration of Study: Department of Anaesthesiology
Gündoğdu, Oğuz, Avcı, Onur, Gundogdu, O., Avci, O.   +3 more
core   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Evaluation of pseudoexfoliation syndrome patients with systemic immune indexes

BMC Ophthalmology
Purpose The aim of this study was to investigate the level of peripheral blood systemic immune indexes in pseudoexfoliation syndrome (PXS) patients and to compare the results with healthy controls.
Ömer Özer, Emin Serbülent Güçlü
doaj   +1 more source

Relationship between systemic immune inflammation index and systemic inflammation response index values and prognosis in patients with burns

Medicine Science
To determine the relationship between systemic immune inflammation index (SyII) and systemic inflammation response index (SyIRI) values and prognosis in adult and pediatric cases treated for deep partial thick and full thick burns.
Serap Samut Bulbul, Alper Ceylan, Metin Ocak, Selim Gorgum, Tolga Pamuk, Mesut Oterkus   +5 more
doaj   +1 more source

A novel predictor in patients with gastrointestinal stromal tumors: Systemic immune-inflammation index (SII)

, 2019
Purpose: Systemic inflammation and immune response are associated with tumors'prognosis. However, there is little information about inflammatory indexes in patients with gastrointestinal stromal tumor (GIST).
YILMAZ, Ali, MİRİLİ, CEM, TEKİN, Salim Başol, BİLİCİ, Mehmet   +3 more
core  

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

Evaluation of Systemic Immune-Inflammation Index for Predicting Mortality in Sepsis Patients [PDF]

Introduction: This study aims to measure the accuracy of Systemic Immune-Inflammation Index (SII) in predicting 28-day mortality in sepsis patients in intensive care unit. Methods:   This study was conducted as a retrospective cohort study. The study was
Palinrungi, Ari Santri, Salam, Syamsul Hilal, Sulkifli Mangga Barani, A.M. Irsyad, Haizah Nurdin, Tanra, Andi Husni, Faisal Muchtar   +5 more
core   +1 more source