Results 101 to 110 of about 661,063 (353)
Exploring the impacts of colostrum on systemic immune development in dairy calves
Journal of Dairy Science: Colostrum provides essential immune components, but its role in shaping neonatal immune development is not fully understood. Twenty-four Holstein calves were randomly assigned to 1 of 3 treatments: fresh colostrum (n = 8), frozen colostrum (n = 8), or ...
M. Cid de la Paz +5 more
doaj +1 more source
Building Climate Change Resilience [PDF]
, 2009 Outlines the foundation's five-year initiative to test and promote local approaches to planning for and adapting to climate change and to raise awareness of the need to invest in building such resilience.
core
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Innovation brokers and their roles in value chain-network innovation: preliminary findings and a research agenda [PDF]
, 2010 Intervention approaches have been implemented in developing countries to enhance farmer's livelihoods through improving their linkages to markets and inclusiveness in agricultural value chains.
Klerkx, L.W.A. +2 more
core +2 more sources
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Unravelling Systemic Risk Dynamics amid Financial Asset Bubbles in Times of Enhanced Volatility [PDF]
Amfiteatru EconomicThis study investigates the dynamics of systemic risk during episodes characterised by asset price bubbles. Specifically, it examines the presence of financial bubbles across all companies included in the Romanian BET Index and isolates these ...
Radu Lupu +4 more
doaj +1 more source
The Journey to R4D: An institutional history of an Australian Initiative on Food Security in Africa [PDF]
, 2016 Internal ...
Bruce, C. +11 more
core +2 more sources
The Minds of Black Women — Impacts on Mental Health and Well-Being Across Collective Identities and Experience [PDF]
, 2020 Limited research investigates how structural and institutional barriers affect Black women's mental health. Further, stereotypes and tropes such as the Angry Black Woman and Strong Black Woman are impactful. Black women's proximity to wellness is largely
Campbell, Kayla
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Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source