Creating Low-carbon Communities: Evaluating the Role of Individual Agency and Systemic Inequality in San Jose, CA [PDF]
, 2019 Following a scholarly need to test compelling community level sociodemographic representations of environmental behaviors and outcomes, a sequential mixed method approach was used to evaluate the connections of human agency and systemic inequalities with
Ronald, Erin Jessica
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FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Assessing the freshwater quality of a large-scale mining watershed : the need for integrated approaches [PDF]
, 2019 Water quality assessments provide essential information for protecting aquatic habitats and stakeholders downstream of mining sites. Moreover, mining companies must comply with environmental quality standards and include public participation in water ...
Arroyo, Nilton Deza +10 more
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FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
The Impacts of Systemic Immune-Inflammation Index on Clinical Outcomes in Gallbladder Carcinoma
Frontiers in Oncology, 2020 Background: Systemic immune-inflammation index (SII) is considered to be a prognostic marker in several cancers. However, the prognostic value of baseline pre-operative SII in gallbladder carcinoma (GBC) has not been evaluated.
Lejia Sun +13 more
doaj +1 more source
The Rockefeller Brothers Fund's Democratic Practice Global Governance Portfolio: Impact Assessment, 20102015 [PDF]
, 2016 This report evaluates the progress of the Rockefeller Brothers Fund (RBF) Democratic Practice–Global Governance (DP-GG) portfolio in the context of the program-specific goal, strategies, and the RBF mission.
Kristen Hite, Melissa Shackleton Dann
core
Impact Assessment of Hypothesized Cyberattacks on Interconnected Bulk Power Systems
, 2018 The first-ever Ukraine cyberattack on power grid has proven its devastation by hacking into their critical cyber assets. With administrative privileges accessing substation networks/local control centers, one intelligent way of coordinated cyberattacks ...
Ginter, Andrew +4 more
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Investigating lupus retention in care to inform interventions for disparities reduction: an observational cohort study. [PDF]
, 2020 BACKGROUND:Systemic lupus erythematous (SLE) disproportionately impacts patients of color and socioeconomically disadvantaged patients. Similar disparities in HIV were reduced through a World Health Organization-endorsed Care Continuum strategy targeting
Ahmad, Umber +8 more
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Insights into the pathogenesis of nicotine addiction. Could a salivary biosensor be useful in Nicotine Replacement Therapy (NRT)? [PDF]
, 2019 Nicotine has gained the attention of the medical community due to its insidious addictive mechanisms which lead to chronic consumption. The multitude of compounds derived from tobacco smoke have local and systemic negative impacts, resulting in a large ...
Alexescu, Teodora G +13 more
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