Results 71 to 80 of about 661,063 (353)

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

A multi-scale risk assessment for tephra fallout and airborne concentration from multiple Icelandic volcanoes – Part 2: Vulnerability and impact [PDF]

open access: yesNatural Hazards and Earth System Sciences, 2014
We perform a multi-scale impact assessment of tephra fallout and dispersal from explosive volcanic activity in Iceland. A companion paper (Biass et al., 2014; "A multi-scale risk assessment of tephra fallout and airborne concentration from multiple ...
C. Scaini   +6 more
doaj   +1 more source

Counterparty Credit Limits: An Effective Tool for Mitigating Counterparty Risk?

open access: yes, 2020
A counterparty credit limit (CCL) is a limit imposed by a financial institution to cap its maximum possible exposure to a specified counterparty. Although CCLs are designed to help institutions mitigate counterparty risk by selective diversification of ...
Gould, Martin D.   +3 more
core  

Banking Fragility & Disclosure: International Evidence [PDF]

open access: yes, 2006
Motivated by recent public policy debates on the role of market discipline in banking stability, the study examines the impact of greater bank disclosure in mitigating the likelihood of systemic banking crisis.
Tadesse, Solomon
core  

Differentiating Among International Investment Disputes [PDF]

open access: yes, 2014
Can investor-state arbitration tribunals, which exercise jurisdiction over limited claims involving discrete parties, render awards that deliver individualized justice while also promoting systemic fairness, predictability and coherence?
Maupin, Julie A.
core   +3 more sources

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Recovered Foam Impact Absorption Systems

open access: yesApplied Sciences
The utilization of foam in contact with individuals often leads to its deterioration, necessitating periodic material changes to prevent degradation and maintain sanitary conditions. Foam, a porous plastic material formed by an aggregation of bubbles, offers lightweight and impact-absorbing properties, yet its porosity and susceptibility to wear pose ...
Sara Marcelino-Sádaba   +4 more
openaire   +3 more sources

Environmental impact assessment of dietary scenarios: a comparison of methodological aspects [PDF]

open access: yes, 2018
Background Dietary patterns have manifold impacts on the environment. • However, studies that assess dietary patterns operate with varying methodological approaches and underlying assumptions, which evoke different, and occasionally even contradicting,
de Boer, Imke J.M.   +4 more
core  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Environmental Impact Computer System [PDF]

open access: yes, 1974
Abstract : This report describes a pilot program in the computer storage and retrieval of environmental impact information. The basic concepts related to implementation and the modes of access to the data are discussed. Also, an outline of the nature of data and the requirements for its management are given, followed by an expression of the reasons for
B. Goettel   +3 more
openaire   +1 more source

Home - About - Disclaimer - Privacy