Results 21 to 30 of about 861,769 (248)

Bone Marrow Plasma Cells Modulate Local Myeloid-Lineage Differentiation via IL-10

Frontiers in Immunology, 2019
Bone marrow plasma cells have been reported to represent a major source of IL-10; however, the impact of plasma cell derived IL-10 in that tissue remains poorly understood.
Lingzhang Meng, Lingzhang Meng, Larissa Nogueira Almeida, Ann-Katrin Clauder, Timo Lindemann, Julia Luther, Christopher Link, Katharina Hofmann, Upasana Kulkarni, David Ming Wong, Jean-Pierre David, Rudolf Armin Manz   +11 more
doaj   +1 more source

Fcγ Receptor IIB Controls Skin Inflammation in an Active Model of Epidermolysis Bullosa Acquisita

Frontiers in Immunology, 2020
Epidermolysis bullosa acquisita (EBA) is an autoimmune skin blistering disease characterized by IgG autoantibodies (aAb) against type VII collagen (COL7).
Balint Kovacs, Balint Kovacs, Jenny Tillmann, Lisa-Christin Freund, Falk Nimmerjahn, Christian D. Sadik, Katja Bieber, Ralf J. Ludwig, Christian M. Karsten, Jörg Köhl, Jörg Köhl   +10 more
doaj   +1 more source

The Identification of a Tumor Infiltration CD8+ T-Cell Gene Signature That Can Potentially Improve the Prognosis and Prediction of Immunization Responses in Papillary Renal Cell Carcinoma

Frontiers in Oncology, 2021
BackgroundCD8+ T cells, vital effectors pertaining to adaptive immunity, display close relationships to the immunization responses to kill tumor cells. Understanding the effect exerted by tumor infiltration CD8+ T cells in papillary renal cell carcinoma (
Jie Wang, Jie Wang, Meiying Huang, Meiying Huang, Peng Huang, Jingjie Zhao, Junhua Tan, Feifan Huang, Ruiying Ma, Yu Xiao, Gao Deng, Liuzhi Wei, Liuzhi Wei, Qiuju Wei, Qiuju Wei, Zechen Wang, Siyuan He, Jiajia Shen, Suren Sooranna, Lingzhang Meng, Jian Song, Jian Song   +21 more
doaj   +1 more source

Transcriptome Profiling Reveals B-Lineage Cells Contribute to the Poor Prognosis and Metastasis of Clear Cell Renal Cell Carcinoma

Frontiers in Oncology, 2021
Although immune therapy can improve the treatment of clear cell renal cell carcinoma (ccRCC) significantly, there are still a large proportion of ccRCC patients who progress to metastasis.
Fafen Yang, Fafen Yang, Jingjie Zhao, Xiuzhuang Luo, Tong Li, Tong Li, Zechen Wang, Qiuju Wei, Qiuju Wei, Heming Lu, Yiliang Meng, Kai Cai, Liuying Lu, Yushi Lu, Lifen Chen, Suren Rao Sooranna, Linxue Luo, Linxue Luo, Jian Song, Jian Song, Lingzhang Meng   +20 more
doaj   +1 more source

Intestinal flora induces depression by mediating the dysregulation of cerebral cortex gene expression and regulating the metabolism of stroke patients

Frontiers in Molecular Biosciences, 2022
Post-stroke depression (PSD) is a common cerebrovascular complication characterized by complex pathogenesis and poor treatment effects. Here, we tested the influence of differentially expressed genes (DEGs), non-targeted metabolites, and intestinal ...
Xuebin Li, Xuebin Li, Guangshun Han, Jingjie Zhao, Xiaohua Huang, Yun Feng, Junfang Huang, Xuequn Lan, Xiaorui Huang, Zechen Wang, Jiajia Shen, Siyuan He, Qiuhao Li, Jian Song, Jian Song, Jie Wang, Jie Wang, Lingzhang Meng, Lingzhang Meng   +18 more
doaj   +1 more source

Overall Structural Alteration of Gut Microbiota and Relationships with Risk Factors in Patients with Metabolic Syndrome Treated with Inulin Alone and with Other Agents: An Open-Label Pilot Study

Mediators of Inflammation, 2022
Objective. The relative contribution of some products with prebiotic effects, such as inulin, together with medications specific to the human gut microbiome has not been comprehensively studied. The present study determined the potential for manipulating
Ruiping Tian, Jiahui Hong, Jingjie Zhao, Dengyuan Zhou, Yangchen Liu, Zhenshan Jiao, Jian Song, Yu Zhang, Lingzhang Meng, Ming Yu   +9 more
doaj   +1 more source

Complement Has Brains—Do Intracellular Complement and Immunometabolism Cooperate in Tissue Homeostasis and Behavior?

Frontiers in Immunology, 2021
The classical liver-derived and serum-effective complement system is well appreciated as a key mediator of host protection via instruction of innate and adaptive immunity.
Natalia Kunz, Claudia Kemper, Claudia Kemper   +2 more
doaj   +1 more source

Systemic Treatment of Vitreous Inflammation [PDF]

Mediators of Inflammation, 2012
Non infectious vitreous inflammation is often vision threatening and can be associated with potentially life-threatening systemic conditions. Treatment is often challenging as it involves systemic medications that can be associated with adverse effects.
John B. Christoforidis, Susie Chang, Angela Jiang, Jillian Wang, Colleen M. Cebulla   +4 more
openaire   +3 more sources

ADAM-10 Regulates MMP-12 during Lipopolysaccharide-Induced Inflammatory Response in Macrophages

Journal of Immunology Research, 2022
A disintegrin and metalloprotease 10 (ADAM-10), a member of the ADAM protease family, has biological activities related to TNF-α activation, cell adhesion, and migration, among other functions.
Yan Jiang, Qiming Gong, Jinmei Huang, Yuanxun Gong, Qiang Tang, Dalong Wei, Qianli Tang, Jingjie Zhao, Jian Song, Lingzhang Meng   +9 more
doaj   +1 more source

S100A9 Derived From Myeloma Associated Myeloid Cells Promotes TNFSF13B/TNFRSF13B-Dependent Proliferation and Survival of Myeloma Cells

Frontiers in Oncology, 2021
Multiple myeloma (MM) is a lethal hematological malignancy characterized by abundant myeloid cells in the microenvironment that fuel tumor progression. But the mechanism by which myeloid cells support myeloma cells has not been fully explored.
Lingzhang Meng, Lingzhang Meng, Qiang Tang, Jingjie Zhao, Zechen Wang, Liuzhi Wei, Liuzhi Wei, Qiuju Wei, Qiuju Wei, Lianfei Yin, Shiguan Luo, Jian Song, Jian Song   +12 more
doaj   +1 more source