Results 31 to 40 of about 3,434,192 (362)

The B Cell Response and Formation of Allergenic and Anti-Allergenic Antibodies in Food Allergy

Biology, 2023
Food allergies are a growing public health concern worldwide, especially in children and young adults. Allergen-specific IgE plays a central role in the pathogenesis of food allergies, but their titers poorly correlate with allergy development.
Christopher C. Udoye, Marc Ehlers, Rudolf A. Manz   +2 more
doaj   +1 more source

Systemic inflammation after stroke: implications for post‐stroke comorbidities

EMBO Molecular Medicine, 2022
Immunological mechanisms have come into the focus of current translational stroke research, and the modulation of neuroinflammatory pathways has been identified as a promising therapeutic approach to protect the ischemic brain.
A. Simats, A. Liesz
semanticscholar   +1 more source

Preoperative systemic inflammation predicts postoperative infectious complications in patients undergoing curative resection for colorectal cancer [PDF]

, 2009
The presence of systemic inflammation before surgery, as evidenced by the glasgow prognostic score (mGPS), predicts poor long-term survival in colorectal cancer. The aim was to examine the relationship between the preoperative mGPS and the development of
Leitch, E.F., Anderson, J.H., J H Anderson, R F McKee, McMillan, D.C., D C McMillan, Moyes, L.H., P G Horgan, McKee, R.F., L H Moyes, E F Leitch, Horgan, P.G.   +11 more
core   +1 more source

Use of Single Cell Transcriptomic Techniques to Study the Role of High-Risk Human Papillomavirus Infection in Cervical Cancer

Frontiers in Immunology, 2022
High-risk human papillomavirus (hrHPV) infection has been associated with a higher probability of progression to cervical cancer. However, several extensive studies have reported that the presence of hrHPV can lead to a better prognosis, but the ...
Lingzhang Meng, Lingzhang Meng, Shengcai Chen, Guiling Shi, Siyuan He, Zechen Wang, Jiajia Shen, Jiajia Wang, Suren Rao Sooranna, Jingjie Zhao, Jian Song, Jian Song, Jian Song   +12 more
doaj   +1 more source

Systemic inflammation response index and systemic immune-inflammation index are associated with severity of acute pancreatitis [PDF]

Ķazaķstannyṇ Klinikalyķ Medicinasy, 2023
Aim: Acute pancreatitis (AP) is a disease with inflammation, and patients present with severe acute upper abdominal pain in emergency departments. AP can result in higher mortality as its clinical severity increases.
Gunay Yildiz, Fatih Selvi, Cihan Bedel, Okkes Zortuk, Umut Ogün Mutlucan   +4 more
doaj   +1 more source

Allergen-Induced C5a/C5aR1 Axis Activation in Pulmonary CD11b⁺ cDCs Promotes Pulmonary Tolerance through Downregulation of CD40

Cells, 2020
Activation of the C5/C5a/C5a receptor 1 (C5aR1) axis during allergen sensitization protects from maladaptive T cell activation. To explore the underlying regulatory mechanisms, we analyzed the impact of C5aR1 activation on pulmonary CD11b+ conventional ...
Konstantina Antoniou, Fanny Ender, Tillman Vollbrandt, Yves Laumonnier, Franziska Rathmann, Chandrashekhar Pasare, Harinder Singh, Jörg Köhl   +7 more
doaj   +1 more source

A Tumor-Infiltration CD8+ T Cell-Based Gene Signature for Facilitating the Prognosis and Estimation of Immunization Responses in HPV+ Head and Neck Squamous Cell Cancer

Frontiers in Oncology, 2021
BackgroundCD8+ T cells, which play a vital role in response to adaptive immunity, are closely related to the immunization responses to kill tumor cells.
Yingning Wu, Yingning Wu, Yingning Wu, Lingzhang Meng, Kai Cai, Jingjie Zhao, Siyuan He, Jiajia Shen, Qiuju Wei, Qiuju Wei, Zechen Wang, Suren Sooranna, Hengguo Li, Jian Song, Jian Song   +14 more
doaj   +1 more source

Parkinson's Disease and Systemic Inflammation [PDF]

Parkinson's Disease, 2011
Peripheral inflammation triggers exacerbation in the central brain's ongoing damage in several neurodegenerative diseases. Systemic inflammatory stimulus induce a general response known as sickness behaviour, indicating that a peripheral stimulus can induce the synthesis of cytokines in the brain.
Carina C. Ferrari, Rodolfo Tarelli
openaire   +3 more sources

Western diet as a trigger of Alzheimer's disease: From metabolic syndrome and systemic inflammation to neuroinflammation and neurodegeneration.

Ageing Research Reviews, 2021
An excess of saturated fatty acids and simple sugars in the diet is a known environmental risk factor of Alzheimer's disease (AD) but the holistic view of the interacting processes through which such diet may contribute to AD pathogenesis is missing.
Angelika Więckowska-Gacek, A. Mietelska-Porowska, M. Wydrych, U. Wojda   +3 more
semanticscholar   +1 more source

The Impact of Systemic Inflammation on Neurodevelopment [PDF]

Trends in Molecular Medicine, 2018
Inflammatory mediators affect the brain during development. Neurodevelopmental disorders such as autism spectrum disorders, cognitive impairment, cerebral palsy, epilepsy, and schizophrenia have been linked to early life inflammation. Recent advances have shown the effects of systemic inflammation on children's neurodevelopment.
Nona M, Jiang, Maureen, Cowan, Shannon N, Moonah, William A, Petri   +3 more
openaire   +2 more sources