Results 21 to 30 of about 3,434,192 (362)

IL-10 revisited in systemic lupus erythematosus

open access: yesFrontiers in Immunology, 2022
IL-10 is a cytokine with pleiotropic functions, particularly known for its suppressive effects on various immune cells. Consequently, it can limit the pathogenesis of inflammatory diseases, such as multiple sclerosis (MS), inflammatory bowel disease ...
Swayanka Biswas   +2 more
doaj   +1 more source

Alterations of the Gut Microbiome in Chinese Zhuang Ethnic Patients with Sepsis

open access: yesMediators of Inflammation, 2022
Objectives. Sepsis is characterized as a dysregulated host immune response to infection and has been known to be closely associated with the gut microbiome.
Jieyang Yu   +8 more
doaj   +1 more source

The Melanocortin System in Control of Inflammation [PDF]

open access: yesThe Scientific World JOURNAL, 2010
Melanocortin peptides, the collective term for α-, β-, and γ-melanocyte-stimulating hormone (α-, β-, γ-MSH) and adrenocorticotropic hormone (ACTH), are elements of an ancient modulatory system. Natural melanocortins derive from the common precursor pro-opiomelanocortin (POMC). Five receptor subtypes for melanocortins (MC1-MC5) are widely distributed in
A. Catania   +5 more
openaire   +4 more sources

The association between systemic inflammation markers and the prevalence of hypertension

open access: yesBMC Cardiovascular Disorders, 2023
Background We conducted a large-scale epidemiological analysis to investigate the associations between systemic inflammation markers and hypertension prevalence. Our aim is to identify potential biomarkers for early detection of hypertension.
Nake Jin   +8 more
semanticscholar   +1 more source

High-Fat, Western-Style Diet, Systemic Inflammation, and Gut Microbiota: A Narrative Review

open access: yesCells, 2021
The gut microbiota is responsible for recovering energy from food, providing hosts with vitamins, and providing a barrier function against exogenous pathogens. In addition, it is involved in maintaining the integrity of the intestinal epithelial barrier,
I. Malesza   +7 more
semanticscholar   +1 more source

Regulation and Dysregulation of Endothelial Permeability during Systemic Inflammation

open access: yesCells, 2022
Systemic inflammation can be triggered by infection, surgery, trauma or burns. During systemic inflammation, an overshooting immune response induces tissue damage resulting in organ dysfunction and mortality. Endothelial cells make up the inner lining of
Katharina E M Hellenthal   +2 more
semanticscholar   +1 more source

Transcriptomic Signatures of Airway Epithelium Infected With SARS-CoV-2: A Balance Between Anti-infection and Virus Load

open access: yesFrontiers in Cell and Developmental Biology, 2021
COVID-19 pneumonia requires effective medical therapies. However, it is a challenge to find therapeutic drugs that not only inhibit viral replication, but also inhibit the accompanying cytokine storm and maintain an appropriate immune response.
Lingzhang Meng   +10 more
doaj   +1 more source

FROM SYSTEMIC INFLAMMATION TO MYOCARDIAL FIBROSIS: THE HFPEF PARADIGM REVISITED.

open access: yesCirculation Research, 2021
In accordance with the comorbidity-inflammation paradigm, comorbidities and especially metabolic comorbidities are presumed to drive development and severity of heart failure with preserved ejection fraction through a cascade of events ranging from ...
W. Paulus, M. Zile
semanticscholar   +1 more source

The complement receptor C5aR2 regulates neutrophil activation and function contributing to neutrophil-driven epidermolysis bullosa acquisita

open access: yesFrontiers in Immunology, 2023
IntroductionThe function of the second receptor for the complement cleavage product C5a, C5aR2, is poorly understood and often neglected in the immunological context.
Daniel L. Seiler   +13 more
doaj   +1 more source

Peri-implantitis and systemic inflammation: A critical update [PDF]

open access: yes, 2023
Peri-implantitis is an inflammatory condition induced by bacterial biofilm that affects the soft and hard tissues surrounding dental implants, compromising the success of implant therapy.
Mansour K. Assery   +7 more
core   +1 more source

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