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The systemic inflammatory response syndrome

open access: yesMicrobes and Infection, 2006
The systemic inflammatory response syndrome (SIRS) is the body's response to an infectious or noninfectious insult. Although the definition of SIRS refers to it as an "inflammatory" response, it actually has pro- and anti-inflammatory components. This review outlines the pathophysiology of SIRS and highlights potential targets for future therapeutic ...
Charles M, Robertson   +1 more
openaire   +3 more sources
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Systemic Inflammatory Response Syndrome

Neonatal Network, 2001
Despite advances in perinatal care in the past decade, sepsis and its complications continue to present problems for the neonate, remaining a major cause of neonatal morbidity and mortality. Sepsis research is focusing on how the neonate (host) responds to bacteria.
Ira Adams-Chapman, Barbara J. Stoll
openaire   +3 more sources

The systemic inflammatory response syndrome

Best Practice & Research Clinical Anaesthesiology, 2004
Sepsis and septic shock are the leading causes of death in intensive care units in developed countries despite recent advances in critical care medicine. Sepsis is the systemic inflammatory response to infection frequently associated with hypoperfusion followed by tissue injury and organ failure. The activation of monocytes/macrophages and neutrophils,
Markus A, Weigand   +3 more
openaire   +3 more sources

Systemic Inflammatory Response Syndrome After Surgery: Mechanisms and Protection

Anesthesia and Analgesia, 2020
The immune system is an evolutionary hallmark of higher organisms that defends the host against invading pathogens and exogenous infections. This defense includes the recruitment of immune cells to the site of infection and the initiation of an ...
A. Margraf   +3 more
semanticscholar   +1 more source

Systemic Inflammatory Response Syndrome

2023
Abstract Systemic inflammatory response syndrome (SIRS) is an overactive defense response of the body to an external or internal stressor. The physiological goal is elimination of insult source via release of acute-phase reactants, leading to significant pro-inflammatory immunological changes.
Maria Gorneva, Anna Tzonkov
openaire   +1 more source

Nitrofurantoin-Induced Systemic Inflammatory Response Syndrome

The American Journal of the Medical Sciences, 2009
Nitrofurantoin is a commonly used antibiotic for the prophylaxis and treatment of urinary tract infections. We report the first case of nitrofurantoin-induced systemic inflammatory response syndrome, an important adverse drug reaction in the setting of what was initially believed to be a recurrent infection.
Christopher J, Forster   +3 more
openaire   +2 more sources

Lipid profile associated with the systemic inflammatory response syndrome and sepsis in critically ill patients.

Nutrition (Burbank, Los Angeles County, Calif.), 2018
OBJECTIVES Changes in lipid profiles occur in systemic inflammatory response syndrome (SIRS), whether due to sepsis or another cause. Hypocholesterolemia associated with hypertriacylglycerolemia can lead to disease severity and higher mortality.
Ana Paula Brigatto Simões Golucci   +3 more
semanticscholar   +1 more source

Systemic Inflammatory Response Syndrome: Septic Shock

Veterinary Clinics of North America: Small Animal Practice, 1994
The systemic inflammatory response syndrome (SIRS) is the body's response to a multitude of chemical mediators. Conditions inciting the release of these mediators include bacterial sepsis, viremia, pancreatitis, trauma, neoplasia, heat stroke, and many others.
D, Purvis, R, Kirby
openaire   +2 more sources

Clopidogrel-Induced Systemic Inflammatory Response Syndrome

Mayo Clinic Proceedings, 2003
Clopidogrel bisulfate, a widely used inhibitor of platelet aggregation, is considered at least as safe as aspirin. We describe a patient who developed a systemic inflammatory response syndrome consisting of high fever, tachycardia, cellulitis-like rash, impaired liver function, and mild leukopenia after receiving clopidogrel before coronary angiography
Ido, Wolf   +3 more
openaire   +2 more sources

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