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The systemic inflammatory response syndrome
The systemic inflammatory response syndrome (SIRS) is the body's response to an infectious or noninfectious insult. Although the definition of SIRS refers to it as an "inflammatory" response, it actually has pro- and anti-inflammatory components. This review outlines the pathophysiology of SIRS and highlights potential targets for future therapeutic ...
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Systemic Inflammatory Response Syndrome
Neonatal Network, 2001Despite advances in perinatal care in the past decade, sepsis and its complications continue to present problems for the neonate, remaining a major cause of neonatal morbidity and mortality. Sepsis research is focusing on how the neonate (host) responds to bacteria.
Ira Adams-Chapman, Barbara J. Stoll
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The systemic inflammatory response syndrome
Best Practice & Research Clinical Anaesthesiology, 2004Sepsis and septic shock are the leading causes of death in intensive care units in developed countries despite recent advances in critical care medicine. Sepsis is the systemic inflammatory response to infection frequently associated with hypoperfusion followed by tissue injury and organ failure. The activation of monocytes/macrophages and neutrophils,
Markus A, Weigand +3 more
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Systemic Inflammatory Response Syndrome After Surgery: Mechanisms and Protection
Anesthesia and Analgesia, 2020The immune system is an evolutionary hallmark of higher organisms that defends the host against invading pathogens and exogenous infections. This defense includes the recruitment of immune cells to the site of infection and the initiation of an ...
A. Margraf +3 more
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Systemic Inflammatory Response Syndrome
2023Abstract Systemic inflammatory response syndrome (SIRS) is an overactive defense response of the body to an external or internal stressor. The physiological goal is elimination of insult source via release of acute-phase reactants, leading to significant pro-inflammatory immunological changes.
Maria Gorneva, Anna Tzonkov
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Nitrofurantoin-Induced Systemic Inflammatory Response Syndrome
The American Journal of the Medical Sciences, 2009Nitrofurantoin is a commonly used antibiotic for the prophylaxis and treatment of urinary tract infections. We report the first case of nitrofurantoin-induced systemic inflammatory response syndrome, an important adverse drug reaction in the setting of what was initially believed to be a recurrent infection.
Christopher J, Forster +3 more
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Nutrition (Burbank, Los Angeles County, Calif.), 2018
OBJECTIVES Changes in lipid profiles occur in systemic inflammatory response syndrome (SIRS), whether due to sepsis or another cause. Hypocholesterolemia associated with hypertriacylglycerolemia can lead to disease severity and higher mortality.
Ana Paula Brigatto Simões Golucci +3 more
semanticscholar +1 more source
OBJECTIVES Changes in lipid profiles occur in systemic inflammatory response syndrome (SIRS), whether due to sepsis or another cause. Hypocholesterolemia associated with hypertriacylglycerolemia can lead to disease severity and higher mortality.
Ana Paula Brigatto Simões Golucci +3 more
semanticscholar +1 more source
Systemic Inflammatory Response Syndrome: Septic Shock
Veterinary Clinics of North America: Small Animal Practice, 1994The systemic inflammatory response syndrome (SIRS) is the body's response to a multitude of chemical mediators. Conditions inciting the release of these mediators include bacterial sepsis, viremia, pancreatitis, trauma, neoplasia, heat stroke, and many others.
D, Purvis, R, Kirby
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Clopidogrel-Induced Systemic Inflammatory Response Syndrome
Mayo Clinic Proceedings, 2003Clopidogrel bisulfate, a widely used inhibitor of platelet aggregation, is considered at least as safe as aspirin. We describe a patient who developed a systemic inflammatory response syndrome consisting of high fever, tachycardia, cellulitis-like rash, impaired liver function, and mild leukopenia after receiving clopidogrel before coronary angiography
Ido, Wolf +3 more
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