Results 41 to 50 of about 635,023 (296)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Síndrome da resposta inflamatória sistêmica: denominação possivelmente aplicável a fenômenos dermatológicos Systemic inflammatory response syndrome: a denomination possibly applied to dermatological phenomena

Anais Brasileiros de Dermatologia, 2007
A síndrome da resposta inflamatória sistêmica consiste na resposta inflamatória aguda mediada por fatores inflamatórios relacionada a sepse e traumatismos extensos.
Maria de Fátima de Medeiros Brito
doaj   +1 more source

Effect of Xenon on Proinflammatory Activation and Apoptosis of Human Neutrophils Under Ex Vivo Conditions

Неотложная медицинская помощь, 2021
Background. The syndrome of systemic inflammatory response, which underlies the damaging effect of factors of infectious and non-infectious genesis, may cause multiple organ failure.
O. A. Grebenchikov, A. K. Shabanov, L. L. Nikolayev, A. I. Shpichko, I. V. Bratishchev, L. Yu. Marchenko, Sh. Zh. Khusainov, R. A. Cherpakov, N. P. Shpichko   +8 more
doaj   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

Systemic inflammatory response syndrome in Sepsis-3: a retrospective study

BMC Infectious Diseases, 2019
Background In the new Sepsis-3 definition, sepsis is defined as “life-threatening organ dysfunction due to a dysregulated host response to infection.” We tested the predictive validity of the systematic inflammatory response syndrome (SIRS) criteria in ...
Wei Zhang, Yan Zheng, Xiaoting Feng, Miao Chen, Yan Kang   +4 more
doaj   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

FEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara, Takayuki Manabe, Mika Jouta, Kiyoshi Kawasaki   +3 more
wiley   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Predictors of systemic inflammatory response syndrome following percutaneous nephrolithotomy

Urology Annals, 2016
Introduction and Objectives: Sepsis remains one of the dreaded complications of percutaneous nephrolithotomy (PCNL). To analyze prospectively the preoperative and intraoperative factors that predict the occurrence of systemic inflammatory response ...
Karunamoorthy Ramaraju, Arun Kumar Paranjothi, Dhinakar Babu Namperumalsamy, Ilamparuthi Chennakrishnan   +3 more
doaj   +1 more source

A Case of Systemic Inflammatory Response Syndrome after Liposuction-assisted Abdominoplasty

Plastic and Reconstructive Surgery, Global Open, 2021
Summary. A 51-year-old woman underwent liposuction-abdominoplasty. After surgery, she developed hypotension and bradycardia, attributed to iatrogenic opioid-intoxication.
Sophie A. Riesmeijer, MD, Berend van der Lei, MD, PhD   +1 more
doaj   +1 more source

Depression and sickness behavior are Janus-faced responses to shared inflammatory pathways [PDF]

, 2012
It is of considerable translational importance whether depression is a form or a consequence of sickness behavior. Sickness behavior is a behavioral complex induced by infections and immune trauma and mediated by pro-inflammatory cytokines.
Anderson, George, Leonard, B, Cai Song, Goehler, Lisa, Gałecki, Piotr, Michael Berk, Michael Maes, Berk, M, Berk, Michael, Maes, Michael, Song, Cai, Leonard, B., Anderson, G, Anderson, G., Leonard, Brian, Maes, M., Piotr Gałecki, Goehler, L., Gałecki, P., Berk, M., Goehler, L, Brian Leonard, Song, C, Gałecki, P, Lisa Goehler, George Anderson, Maes, M, Song, C.   +27 more
core   +1 more source