Results 101 to 110 of about 1,405,405 (194)

Work Productivity Loss and Activity Impairment in Parents of Children With Juvenile Idiopathic Arthritis

ACR Open Rheumatology, Volume 8, Issue 10, October 2026.
Objective To determine the impact of juvenile idiopathic arthritis (JIA) on work productivity loss and daily activities of parents. Methods The multicenter Canada‐Netherlands Understanding Childhood Arthritis Network (UCAN) CAN‐DU and CURE study captures consecutive clinical and patient‐reported data for patients and parents since 2019.
Deborah A. Marshall, Rodrigo Dal Ben, Gillian R. Currie, Rae S. M. Yeung, Sebastiaan J. Vastert, Nico Wulffraat, Joost F. Swart, Susanne Benseler, on behalf of the UCAN CAN‐DU and UCAN CURE Consortia, Rae Yeung, Shirley Tse, Deborah Levy, Ronald Laxer, Brian Feldman, Elizaveta Limenis, Ruud Verstegen, Lynn Spiegel, Rayfel Schneider, Evelyn Rozenblyum, Jennifer Ji Young Lee, Alisa Rachlis, Susanne Benseler, Nicole Johnson, Muhammed Dhalla, Paivi Miettunen, Heinrike Schmeling, Marinka Twilt, Rebeka Stevenson, Deborah Marshall, Andrea Human, David Cabral, Jaime Guzman, Kim Morishita, Kristin Houghton, Lori Tucker, Tommy Gerschman, Herman Tam, Mercedes Chan, Ross Petty, Roman Jurencak, Nadia Luca, Ciarán Duffy, Tala El Tal, Roberta Berard, Jonathan Park, Erkan Demirkaya, Lily Lim, Adam Huber, Bianca Lang, Elizabeth Stringer, Chelsea DeCoste, Suzanne Ramsey, Dax G. Rumsey, Daniah Basodan, Lillian Lim, Hon Yan Ng, Jeanine McColl, Tara McGrath, Michelle Batthish, Tania Cellucci, Liane Heale, Claire LeBlanc, Gaëlle Chédeville, Rosie Scuccimarri, Sarah Campillo, Piya Lahiry, Paul Dancey, Nickolas Blanchette, Alan Rosenberg, Mehul Jariwala, Tristan Kerr, Kate Neufeld, Clare Hutchinson, Gordon Soon, Dieneke Schonenberg, Mariken Gruppen, Merlijn van den Berg, Giske Biesbroek, Philomine van Pelt, Marleen Verkaaik, Sylvia Kamphuis, Danielle Brinkman, Petra Hissink Muller, Ellen Schatorje, Esther Hoppenreijs, Annet van Royen‐Kerkhof, Sebastiaan Vastert, Berent Prakken, Erika Van Nieuwenhove, Joost Swart, Marc Jansen, Nico Wulffraat, Elizabeth Legger, Wineke Armbrust, Joseph Cafazzo, Maarten IJzerman, Alexander Mosoiu, Amy Xu, Arthur Cheng, Bruno Pereira, Trang Duong, Harper Cheng, Brenleigh Jebb, Gillian R. Currie, Rodrigo Dal Ben, Ravneet Sran, Elodie Boudes, Michelle Kip, Sytze de Rook, Regina de Geus   +109 more
wiley   +1 more source

Rethinking Common Diagnoses: Idiopathic Multicentric Castleman Disease Presenting as TAFRO Syndrome: A Case Report

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT Idiopathic multicentric Castleman disease (TAFRO subtype) can mimic common differentials. High suspicion is required for chronic systemic symptoms and generalized lymphadenopathy. As fine‐needle aspiration is often non‐diagnostic, early excisional biopsy is important.
Divita Rohatgi, Annesha Chakraborty, Sourav Kumar, Anurag Rohatgi   +3 more
wiley   +1 more source

Acute Pustular Facial Eruption in a 5‐Year‐Old Boy

Pediatric Dermatology, EarlyView.
Naia Oillarburu, Magalie Coco‐Viloin, Emilie Tournier, Juliette Mazereeuw‐Hautier, Maella Severino‐Freire   +4 more
wiley   +1 more source

Mucosal‐Associated Invariant T Cells in Health and Disease

MedComm, Volume 7, Issue 10, October 2026.
The roles of MAIT cells in health and disease and their therapeutic applications. In healthy individuals, riboflavin metabolites secreted by commensal bacteria at mucosal sites are presented by MR1, leading to the activation of MAIT cells. Activated MAIT cells can maintain the barrier integrity of mucosal tissues in a steady state or migrate to the ...
Yu Zhao, Feng‐Mi Ou, Dan Liang, Yang Gao, Qing‐Qing Li, Yi‐Qun Kuang   +5 more
wiley   +1 more source

The role of IL-1 inhibition in systemic juvenile idiopathic arthritis: current status and future perspectives

, 2018
Nataša Toplak,1,2 Štefan Blazina,1 Tadej Avčin1,2 1Department of Allergology, Rheumatology and Clinical Immunology, University Children’s Hospital, University Medical Centre Ljubljana, Ljubljana, Slovenia; 2Faculty of Medicine ...
Avčin T, Blazina Š, Toplak N
core  

Two- and 3-year outcomes of the childhood arthritis and rheumatology research alliance FiRst Line Options for sJIA Treatment (FROST) trial

Pediatric Rheumatology Online Journal
Background Systemic juvenile idiopathic arthritis (sJIA) is a severe autoinflammatory disease associated with substantial morbidity, including macrophage activation syndrome (MAS), sJIA-associated lung disease, and glucocorticoid (GC)-related toxicity ...
Timothy Hahn, George Tomlinson, Yukiko Kimura, Vincent Del Gaizo, Timothy Beukelman, and the CARRA FROST Investigators   +5 more
doaj   +1 more source

Iron and Other Metal Ions in Human Health and Disease

MedComm, Volume 7, Issue 10, October 2026.
Iron, copper, zinc, and calcium orchestrate cellular function through distinct yet cooperative mechanisms: redox‐active iron and copper cycle between oxidation states to act as Fenton catalysts and electron carriers in oxidative phosphorylation (OXPHOS); redox‐inert zinc serves as a structural component of zinc‐finger proteins and a catalytic cofactor ...
Xiaofeng Dai, Jitian Li
wiley   +1 more source

Biologic therapies in systemic juvenile idiopathic arthritis

, 2016
Introduction: Systemic juvenile idiopathic arthritis (SJIA) is characterized by fever, rash, arthritis, lymphadenopathy, hepatosplenomegaly, and serositis. It is frequently considered an autoinflammatory syndrome. There is interplay between different pro-
BATU AKAL, EZGİ DENİZ
core   +1 more source

Drug‐Induced Liver Injury During Treatment With Tocilizumab: A Case Report of an Atypical Pattern Lesion

Pharmacology Research &Perspectives, Volume 14, Issue 5, October 2026.
ABSTRACT Tocilizumab is an interleukin‐6 (IL‐6) receptor antagonist indicated for various rheumatologic conditions. While hepatotoxicity is a recognized adverse effect, it predominantly manifests as hepatocellular injury. We report a rare case of drug‐induced liver injury (DILI) presenting with a cholestatic pattern and cholangitis features in a 75 ...
Louis‐Edmond Barbaro, Nouha Ben Othman, Delphine Viard, Fanny Rocher, Elliot Ewig, Raja Mroue, Claire Amigues, Alexandre O. Gérard   +7 more
wiley   +1 more source

Treatment of refractory juvenile idiopathic arthritis via pulse therapy using methylprednisolone and cyclophosphamide

São Paulo Medical Journal
CONTEXT: Patients with refractory juvenile idiopathic arthritis can benefit from aggressive therapy. CASE REPORT: We followed the clinical course of 4 patients (2 male, 2 female) aged 9.1-17.8 years (mean of 14.5 years) with polyarticular onset of ...
Tania Caroline Monteiro de Castro, Maria Teresa Terreri, Claudio Len, Maria Odete Esteves Hilário   +3 more
doaj   +1 more source