Results 81 to 90 of about 1,405,405 (194)

Early changes in gene expression and inflammatory proteins in systemic juvenile idiopathic arthritis patients on canakinumab therapy

, 2021
Background: Canakinumab is a human anti-interleukin-1 beta (IL-1 beta) monoclonal antibody neutralizing IL-1 beta-mediated pathways. We sought to characterize the molecular response to canakinumab and evaluate potential markers of response using samples ...
Quartier, Pierre, Gerloni, Valeria, Terreri, Maria, Ruperto, Nicolino, Brachat, Arndt H., Grom, Alexei A., Abrams, Ken, Brunner, Hermine I., Harel, Liora, Schneider, Rayfel, Martini, Alberto, McCann, Liza, Ozdogan, Huri, Valentin, Marie-Anne, Lopez-Benitez, Jorge M., Joos, Rik, Schumacher, Martin, Gram, Hermann, Rutkowska-Sak, Lidia, Wulffraat, Nico, Houghton, Kristin, Bek, Stephan, Nirmala, Nanguneri R., Kingsbury, Daniel, Brik, Riva, Lovell, Daniel J.   +25 more
core   +1 more source

Management of Non‐Plaque‐Induced Gingival Conditions: A Systematic Review—Part 2: Inflammatory and Immune Conditions; Neoplasms; and Gingival Pigmentation

Journal of Clinical Periodontology, EarlyView.
ABSTRACT Aims This systematic review assesses current evidence on the management of non‐plaque (dental biofilm)‐induced gingival diseases and conditions (NPIGDs), including (i) inflammatory and immune conditions, (ii) neoplasms and (iii) gingival pigmentations.
Maria Clotilde Carra, Cecile Wasielewski, Bruno Špiljak, Maja Sabalić‐Schoener, Sebastien Jungo, Ivan Alajbeg   +5 more
wiley   +1 more source

INFLIXIMAB IN TREATMENT OF ACTIVE JUVENILE ARTHRITIS

Вопросы современной педиатрии, 2012
The article includes the results of observation of patients with resistant forms of juvenile arthritis, who have received treatment with infliximab in the period of time since 2004 till 2011.
E. S. Zholobova, O. Yu. Konopel'ko, D. V. Dagbaeva, A. V. Bunin, O. S. Rozvadovskaya, M. N. Nikolaeva, V. Ya. El'yashevich   +6 more
doaj   +1 more source

Tooth Wear Severity and Temporomandibular Joint Degenerative Findings on Cone‐Beam Computed Tomography: A Cross‐Sectional Study in Adults

Journal of Oral Rehabilitation, EarlyView.
In 80 adults with TMD symptoms (160 joints), tooth wear was scored clinically and TMJ degeneration was assessed on CBCT. Adjusted analyses showed no association with osteophytes, erosion, subchondral cysts, or definite osteoarthritis, indicating that tooth wear alone does not predict TMJ degeneration.
Gizem Altundal, Ceyda Deniz Özdemir, Ece Zorlu, Fatma Yüce, Sibel Biren   +4 more
wiley   +1 more source

Myeloid A20 Regulates Periodontal Tissue Integrity and Temporomandibular Joint Structure

Journal of Periodontal Research, EarlyView.
Dysregulation of A20 signaling has been implicated in several immune‐mediated diseases, including rheumatoid arthritis and psoriasis, conditions characterized by excessive NF‐κB activation and inflammatory tissue damage. The structural alterations observed in this model suggest that impaired regulation of innate immune signaling may increase ...
Karol Alí Apaza Alccayhuaman, Patrick Heimel, Toni Dobsak, Stefan Tangl, Geert van Loo, Dieter D. Bosshardt, Reinhard Gruber   +6 more
wiley   +1 more source

Occurrence of infections in dogs receiving ciclosporin in a single‐centre UK referral population

Journal of Small Animal Practice, EarlyView.
Objectives The study aimed (a) to describe the occurrence and nature of new infections in dogs receiving oral ciclosporin and (b) to identify any risk factors associated with the development of a new infection whilst receiving ciclosporin. Materials and Methods In this retrospective cohort study, medical records of dogs presented to a private UK ...
S. Dormon, J. Walker, G. Gallow, L. Goonan, T. Sparks, A. Paul   +5 more
wiley   +1 more source

Treatment of Juvenile Idiopathic Arthritis-Associated Uveitis

, 2016
Pediatric uveitis may be a serious health problem because of the lifetime burden of vision loss due to severe complications if the problem is not adequately treated.
İlknur Tuğal-Tutkun
core   +1 more source

Arthritis and other musculoskeletal conditions across the life stages [PDF]

, 2014
Arthritis and other musculoskeletal conditions affect an estimated 6.1 million Australians across all ages, this report finds. Summary Arthritis and other musculoskeletal conditions are common, affecting an estimated 6.1 million Australians (28% of the

core  

Does early treatment of macrophage activation syndrome prevent fatal outcome in patients with severe systemic juvenile idiopathic arthritis?

, 2014
Macrophage activation syndrome (MAS), a rare complication of various diseases, mainly systemic inflammatory connective tissue disorders, is being increasingly recognized.
Teresa Kołcun-Penkowska, Marzena Janczewska   +1 more
core   +1 more source

Understanding the Reproductive Life Planning Experiences of People With Disabilities in Ontario, Canada: A Qualitative Exploration

Perspectives on Sexual and Reproductive Health, EarlyView.
ABSTRACT Introduction Reproductive life planning can be a valuable component of reproductive health promotion. However, little is known about attitudes, desires, and intentions regarding pregnancy among people with disabilities. This exploratory qualitative study aimed to understand the reproductive life planning experiences of women and gender‐diverse
Momina Khan, Hilary K. Brown, Yona Lunsky, Lesley A. Tarasoff   +3 more
wiley   +1 more source