Results 61 to 70 of about 17,216 (186)

Update on Non‐Biological and RNA‐Based Therapeutics in Chronic Inflammatory Diseases: Precision Medicine Through Small Molecules: An EAACI Position Paper

Allergy, EarlyView.
ABSTRACT In the last decades, critical advancements in research technology and knowledge on disease mechanisms steered therapeutic approaches for chronic inflammatory diseases towards unprecedented target specificity. For allergic and chronic lung diseases, biologic drugs pioneered this goal, acquiring on the way—through the clinical use of monoclonal ...
F. Roth‐Walter, I. M. Adcock, C. Benito‐Villalvilla, R. Bianchini, L. Bjermer, G. Caramori, L. Cari, K. F. Chung, Z. Diamant, I. Eguiluz‐Gracia, E. F. Knol, M. Jesenak, F. Levi‐Schaffer, G. Nocentini, L. O'Mahony, O. Palomares, F. Redegeld, M. Sokolowska, B. Van Esch, M. Zurlo, C. Stellato   +20 more
wiley   +1 more source

Rilonacept pharmacokinetics in children with systemic juvenile idiopathic arthritis [PDF]

The Journal of Clinical Pharmacology, 2014
Systemic juvenile idiopathic arthritis (sJIA) is a disease characterized by arthritis in children
Julie Autmizguine, Michael Cohen‐Wolkowiez, Norman Ilowite, null for the RAPPORT investigators   +3 more
openaire   +2 more sources

Temporomandibular joint disorders as the only manifestation of juvenile idiopathic arthritis: a case report

Einstein (São Paulo)
Juvenile idiopathic arthritis is a term used to include all chronic childhood arthritis of unknown etiology. It is characterized by chronic inflammation persisting for at least 6 weeks, beginning before 16 years of age.
José Renato Ribeiro Pinto, Irineu Gregnanin Pedron, Estevam Rubens Utumi, Milton Edson Miranda, Elisa Cruz Pereira Pinto, Leopoldo Penteado Nucci   +5 more
doaj   +1 more source

Inflammation Unchecked: Concurrent Kawasaki Disease and Stevens‐Johnson Syndrome in an 18‐Month‐Old Child

Arthritis Care &Research, EarlyView.
Catherine Deffendall, Jodi Backalar, Elizabeth Acevedo Zapata, Adriana Della Porta, Lorin Bibb, Tyler Reese, Charlotte M. Brown   +6 more
wiley   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

Management of Non‐Plaque‐Induced Gingival Conditions: A Systematic Review—Part 2: Inflammatory and Immune Conditions; Neoplasms; and Gingival Pigmentation

Journal of Clinical Periodontology, EarlyView.
ABSTRACT Aims This systematic review assesses current evidence on the management of non‐plaque (dental biofilm)‐induced gingival diseases and conditions (NPIGDs), including (i) inflammatory and immune conditions, (ii) neoplasms and (iii) gingival pigmentations.
Maria Clotilde Carra, Cecile Wasielewski, Bruno Špiljak, Maja Sabalić‐Schoener, Sebastien Jungo, Ivan Alajbeg   +5 more
wiley   +1 more source

MEFV mutations in systemic onset juvenile idiopathic arthritis [PDF]

Rheumatology, 2008
Autoinflammatory diseases constitute a large spectrum of monogenic diseases like FMF or cryopyrin-associated periodic syndromes (CAPS) and complex genetic trait diseases such as systemic onset juvenile idiopathic arthritis (SoJIA). An increased rate of MEFV mutations has been shown among patients with PAN and HSP, in populations where FMF is frequent ...
N A, Ayaz, S, Ozen, Y, Bilginer, M, Ergüven, E, Taşkiran, E, Yilmaz, N, Beşbaş, R, Topaloğlu, A, Bakkaloğlu   +8 more
openaire   +2 more sources

Is Still's Disease an Autoinflammatory Syndrome?

International Journal of Inflammation, 2012
Systemic juvenile idiopathic arthritis (sJIA), formerly called Still's disease, is officially classified as a subset of juvenile idiopathic arthritis (JIA).
Linda Rossi-Semerano, Isabelle Koné-Paut   +1 more
doaj   +1 more source

Systemic-onset juvenile idiopathic arthritis in a child with thalassemia major

Journal of Applied Hematology, 2018
Patients with thalassemia are known to have an increased risk of immune-mediated illness. This increased risk may be due to a genetic predisposition or underlying immunological abnormalities.
Pitta Mary Dayana, Rachel Ranitha Peterson, Madhuri Maganthi, Jacob Mathews Vahaneyil   +3 more
doaj   +1 more source

Myeloid A20 Regulates Periodontal Tissue Integrity and Temporomandibular Joint Structure

Journal of Periodontal Research, EarlyView.
Dysregulation of A20 signaling has been implicated in several immune‐mediated diseases, including rheumatoid arthritis and psoriasis, conditions characterized by excessive NF‐κB activation and inflammatory tissue damage. The structural alterations observed in this model suggest that impaired regulation of innate immune signaling may increase ...
Karol Alí Apaza Alccayhuaman, Patrick Heimel, Toni Dobsak, Stefan Tangl, Geert van Loo, Dieter D. Bosshardt, Reinhard Gruber   +6 more
wiley   +1 more source