Complement Activation in Patients With Probable Systemic Lupus Erythematosus and Ability to Predict Progression to American College of Rheumatology-Classified Systemic Lupus Erythematosus. [PDF]
ObjectiveTo evaluate the frequency of cell-bound complement activation products (CB-CAPs) as a marker of complement activation in patients with suspected systemic lupus erythematosus (SLE) and the usefulness of this biomarker as a predictor of the ...
Alexander, Roberta Vezza +12 more
core +2 more sources
Ocular changes due to the treatment of juvenile systemic lupus erythematosus [PDF]
OBJECTIVE: To assess retrospectively the ocular changes in children and adolescents with juvenile systemic lupus erythematosus (JSLE) in a tertiary pediatric rheumatology service.
Finamor, Luciana Peixoto dos Santos +6 more
core +3 more sources
The role of apoptosis proteins and complement components in the etiopathogenesis of systemic lupus erythematosus [PDF]
Systemic lupus erythematosus is a prototypical autoimmune disease characterized by the deregulation of T and B cells, tissue infiltration by mononuclear cells, tissue damage and the production of autoantibodies.
KISS, Maria Helena Bittencourt +1 more
core +5 more sources
Rhupus arthropathy as the presenting manifestation in Juvenile SLE: a case report [PDF]
An 8.5-year-old girl was referred with swelling of both knees lasting for two years. ANA was found as negative. She was diagnosed as oligoarticular JIA. After two years of follow-up, thrombocytopenia was detected during routine screening.
Ayse Arlı, Erbil Unsal, Hakkı Akman
core +3 more sources
Vitamin D supplementation in the pediatric rheumatology clinic. [PDF]
Vitamin D is capturing the attention of healthy and chronically ill populations for its potential skeletal and nonskeletal benefits. New information suggesting a role in immune modulation has led to a surge of interest among rheumatologists. Although the
Burnham, Jon M, von Scheven, Emily
core +3 more sources
Objective To determine whether there is an association between the profile of cognitive dysfunction and academic outcomes in patients with juvenile systemic lupus erythematosus (JSLE).
Renan Bazuco Frittoli +5 more
doaj +1 more source
A discrete cluster of urinary biomarkers discriminates between active systemic lupus erythematosus patients with and without glomerulonephritis. [PDF]
BackgroundManagement of lupus nephritis (LN) would be greatly aided by the discovery of biomarkers that accurately reflect changes in disease activity.
Avila-Casado, Carmen +10 more
core +3 more sources
Tocilizumab, an anti-interleukin-6 (IL-6) agent, is indicated as a treatment for several autoimmune or inflammatory diseases, including rheumatoid arthritis and juvenile idiopathic arthritis (JIA). IL-6 plays roles in both immune system dysregulation and
Ju-Yang Jung +3 more
doaj +1 more source
Evaluation of magnetic resonance imaging abnormalities in juvenile onset neuropsychiatric systemic lupus erythematosus. [PDF]
The aim of this study was to describe the abnormalities identified with conventional MRI in children with neuropsychiatric systemic lupus erythematosus (NPSLE).
Al-Obaidi, M +8 more
core +1 more source
FRI0627-HPR COGNITIVE DISORDERS IN SYSTEMIC LUPUS ERYTHEMATOSUS WITH JUVENILE-ONSET: ONE SINGLE CENTER EXPERIENCE [PDF]
Background: Juvenile-onset SLE (jSLE) is a more aggressive disease than in adults due to several reasons including cognitive dysfunction, significantly affected the compliance and social rehabilitation of patients (pts). Objectives: To analyze the cognitive, emotional and communicative status of pts with jSLE.
M. Kaleda, N. Stepanenko, I. Nikishina
openaire +1 more source

