Juvenile-onset multifocal osteonecrosis in systemic lupus erythematosus
Abstract Rationale: Osteonecrosis (ON) is a devastating illness that leads to bone ischemia and potential joint destruction. Systemic lupus erythematosus (SLE) is a chronic, autoimmune disease, with multi-system involvement which is closely associated with occurrence of ON.
Jin, Wenyuan, Yang, Xinghui, Lu, Meiping
openaire +2 more sources
Neuropsychiatric involvement in juvenile-onset systemic lupus erythematosus (jSLE)
AbstractSystemic lupus erythematosus (SLE) is a rare autoimmune/inflammatory disease with significant morbidity and mortality. Approximately 15–20% of SLE patients develop the disease during childhood or adolescence (juvenile-onset SLE/jSLE). Patients with jSLE exhibit more variable and severe disease when compared to patients with disease-onset during
Valentina Natoli +3 more
openaire +3 more sources
The role of neutrophil apoptosis in juvenile‐onset systemic lupus erythematosus [PDF]
AbstractObjectiveAccumulation of apoptotic cells may lead to the development of systemic lupus erythematosus (SLE) through a breakdown in immune tolerance. Altered neutrophil apoptosis may contribute to nuclear autoantigen exposure, ultimately leading to autoantibody generation.
Angela, Midgley +4 more
openaire +2 more sources
IgG anti-apolipoprotein A-1 antibodies in patients with systemic lupus erythematosus are associated with disease activity and corticosteroid therapy: an observational study. [PDF]
IgG anti-apolipoprotein A-1 (IgG anti-apoA-1) antibodies are present in patients with systemic lupus erythematosus (SLE) and may link inflammatory disease activity and the increased risk of developing atherosclerosis and cardiovascular disease (CVD) in ...
Davari, M +19 more
core +1 more source
Percentages of lymphocyte subsets in the juvenile-onset systemic lupus erythematosus patients.
Percentages of lymphocyte subsets in the juvenile-onset systemic lupus erythematosus patients.
Butsabong Lerkvaleekul (12055191) +5 more
core +1 more source
The role of the host—Neutrophil biology
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple +4 more
wiley +1 more source
Predictors of remission on therapy in the juvenile-onset systemic lupus erythematosus patients.
Predictors of remission on therapy in the juvenile-onset systemic lupus erythematosus patients.
Butsabong Lerkvaleekul (12055191) +5 more
core +1 more source
Lack of the long pentraxin PTX3 promotes autoimmune lung disease but not glomerulonephritis in murine systemic lupus erythematosus. [PDF]
The long pentraxin PTX3 has multiple roles in innate immunity. For example, PTX3 regulates C1q binding to pathogens and dead cells and regulates their uptake by phagocytes. It also inhibits P-selectin-mediated recruitment of leukocytes.
Mantovani Alberto +32 more
core +1 more source
Demographic, clinical, and laboratory parameters of the juvenile-onset systemic lupus erythematosus patients.
Butsabong Lerkvaleekul (12055191) +5 more
core +1 more source
Serum calcification propensity is independently associated with disease activity in systemic lupus erythematosus. [PDF]
Systemic lupus erythematosus (SLE) is associated with severe cardiovascular complications. The T50 score is a novel functional blood test quantifying calcification propensity in serum.
Chizzolini, Carlo +50 more
core +3 more sources

