Results 41 to 50 of about 67,974,619 (226)

Off-label use of tocilizumab to treat non-juvenile idiopathic arthritis in pediatric rheumatic patients: a literature review

Pediatric Rheumatology Online Journal, 2018
Tocilizumab, an anti-interleukin-6 (IL-6) agent, is indicated as a treatment for several autoimmune or inflammatory diseases, including rheumatoid arthritis and juvenile idiopathic arthritis (JIA). IL-6 plays roles in both immune system dysregulation and
Ju-Yang Jung, Moon-Young Kim, Chang-Hee Suh, Hyoun-Ah Kim   +3 more
doaj   +1 more source

The Swiss Systemic lupus erythematosus Cohort Study (SSCS) - cross-sectional analysis of clinical characteristics and treatments across different medical disciplines in Switzerland [PDF]

, 2014
OBJECTIVES: To describe disease characteristics and treatment modalities in a multidisciplinary cohort of systemic lupus erythematosus (SLE) patients in Switzerland.
Stoll, T., Cohen, Clemens, Chizzolini, Carlo, Swiss Systemic Lupus Erythematosus Cohort Study Group, Hunziker, Thomas, Hauser, T., Clemens Cohen, Von Kempis, J., Stoll, Thomas, Katrin Koenig, Gayet-Ageron, Angèle, Carlo Chizzolini, Dayer, E., Koenig, K., Hunziker, T., Gregor Lindner, Chizzolini, C., François Spertini, Trendelenburg, M., Leimgruber, A., Lindner, Gregor, Ribi, C., Von Kempis, Johannes, Thomas Hauser, Eric Dayer, Annette Leimgruber, Petra Otto, Dayer, Eric, Koenig, Katrin, Cohen, C., Leimgruber, Annette, Spertini, F., Hauser, Thomas, Eisenberger, Ute, Thomas Stoll, Lindner, G., Otto, P., Ribi, Camillo, Eisenberger, U., Ute Eisenberger, Thomas Hunziker, Marten Trendelenburg, Johannes Von Kempis, Trendelenburg, Marten, Otto, Petra, Camillo Ribi, Spertini, François, Gayet-Ageron, A., Angèle Gayet-Ageron, Dayer E, Spertini F, Chizzolini C, Koenig K, Hunziker T, Otto P, Hauser T, Stoll T, Lindner G, Gayet-Ageron A, Eisenberger U, Leimgruber A, Trendelenburg M, Von Kempis J, Ribi C, Cohen C   +64 more
core   +1 more source

Risk factors for subsequent lupus nephritis in patients with juvenile-onset systemic lupus erythematosus: a retrospective cohort study

Pediatric Rheumatology Online Journal, 2023
Background Lupus nephritis (LN) is a crucial organ involvement in systemic lupus erythematosus (SLE). Patients with LN have higher morbidity and mortality rates than those without.
Tzu-Chuan Hsu, Yao-Hsu Yang, Li-Chieh Wang, Jyh-Hong Lee, Hsin-Hui Yu, Yu-Tsan Lin, Ya-Chiao Hu, Bor-Luen Chiang   +7 more
doaj   +1 more source

Bone mineral density in juvenile onset Systemic lupus erythematosus

Indian Pediatrics, 2015
To compare bone mineral density in patients with juvenile-onset Systemic lupus erythematosus and healthy controls.Serial bone mineral density measurements in 27 patients with juvenile-onset systemic lupus were compared to 97 healthy age-matched controls.All patients with juvenile-onset had low bone mineral density scores at initial assessment that ...
R, Abdwani, E, Abdulla, S, Yaroubi, H, Bererhi, I, Al-Zakwani   +4 more
openaire   +2 more sources

Systemic lupus erythematosus with juvenile onset: current status of the problem (literature review)

Современная ревматология
Patients with juvenile-onset systemic lupus erythematosus (jSLE) account for up to 25% of all SLE patients. The main difference between jSLE and SLE in adults is the greater role of genetic factors in the pathogenesis, higher activity, earlier ...
M. I. Kaleda, I.  P. Nikishina
doaj   +1 more source

Oral Ulcers in Juvenile-Onset Systemic Lupus Erythematosus: A Review of the Literature [PDF]

American Journal of Clinical Dermatology, 2017
Oral ulcers are the most common mucosal sign in juvenile-onset systemic lupus erythematosus (JSLE). The ulcers are one of the key clinical features; however, the terminology of oral ulcers, especially in JSLE patients, is often vague and ill-defined. In fact, there are several clinical manifestations of oral ulcers in JSLE, and some lesions occur when ...
Rodsaward, Pongsawat, Prueksrisakul, Titipong, Deekajorndech, Tawatchai, Edwards, Steven W, Beresford, Michael W, Chiewchengchol, Direkrit   +5 more
openaire   +2 more sources

Exercise as adjunctive therapy for systemic lupus erythematosus [PDF]

, 2021
This is a protocol for a Cochrane Review (intervention). The objectives are as follows: To evaluate the safety and effectiveness of structured exercise interventions for adults with systemic lupus ...
Greene, David, Cameron, Melainie, O'Neill, Sean, Frade, Stephanie, David Greene, Sean O'Neill, Stephanie Frade, Melainie Cameron   +7 more
core   +1 more source

Belimumab in the treatment of systemic lupus erythematosus with juvenile onset: Results of a single-center retrospective study

Научно-практическая ревматология
The treatment of systemic lupus erythematosus with juvenile onset (jSLE) remains a difficult task, taking into account the more aggressive course of the disease, requiring the appointment of various therapy regimens, including mainly a combination of ...
Maria I. Kaleda, Irina P. Nikishina, Tamari N. Pachkoria, Anna N. Shapovalenko   +3 more
doaj   +1 more source

Calprotectin in rheumatic diseases: a review

Rheumatology, 2016
Calprotectin also known as MRP8/14 or S100A8/A9 is a heterodimeric complex of two S100 calcium-binding proteins: myeloid-related protein 8 (MRP-8 or S100A8) and MRP-14 (or S100A9). At present, according to many authors, it is considered that calprotectin
Magdalena Kopeć-Mędrek, Małgorzata Widuchowska, Eugeniusz J. Kucharz   +2 more
doaj   +1 more source

Problems of systemic connective tissue diseases of childhood in historical perspective

Научно-практическая ревматология
The relevance of study systemic connective tissue diseases with juvenile onset for modern medicine is determined by the trend towards their growth in the population, the difficulty of early diagnosis, the rapid development of disability and a poor life ...
M. I. Kaleda, I. P. Nikishina
doaj   +1 more source