Results 31 to 40 of about 53,292,385 (218)
Neuropsychiatric involvement in juvenile-onset systemic lupus erythematosus: A multicenter study
Neuropsychiatric (NP) involvement is a restricted area in juvenile-onset systemic lupus erythematosus (jSLE).To investigate the prevalence, demographic and clinical features, and outcomes of the neurological involvement in the Turkish jSLE population.This study was based upon 24 referral centers' SLE cohorts, multicenter and multidisciplinary network ...
Poyrazoğlu, Muammer H +59 more
openaire +12 more sources
Belimumab : a technological advance for systemic lupus erythematosus patients? Report of a systematic review and meta-analysis [PDF]
Objectives: To undertake a systematic review and meta-analysis to investigate clinical effectiveness of belimumab for patients with systemic lupus erythematosus (SLE) and antinuclear and/or anti-double-stranded DNA (dsDNA) autoantibodies.
Hartley, Louise +17 more
core +1 more source
Objective The transition from pediatric to adult rheumatology care represents a particularly vulnerable time for patients with juvenile idiopathic arthritis (JIA) and childhood‐onset systemic lupus erythematosus (cSLE).
Jeanine McColl +11 more
doaj +1 more source
ICF Core Sets: how to specify impairment and function in systemic lupus erythematosus [PDF]
The World Health Organization’s International Classification of Function (ICF) is a tool to characterize and illuminate better the full of array of problems a patient faces when affected by disease.
Pisetsky, D.S. +7 more
core +1 more source
The Swiss Systemic lupus erythematosus Cohort Study (SSCS) - cross-sectional analysis of clinical characteristics and treatments across different medical disciplines in Switzerland [PDF]
OBJECTIVES: To describe disease characteristics and treatment modalities in a multidisciplinary cohort of systemic lupus erythematosus (SLE) patients in Switzerland.
Stoll, T. +48 more
core +1 more source
Objective To determine whether there is an association between the profile of cognitive dysfunction and academic outcomes in patients with juvenile systemic lupus erythematosus (JSLE).
Renan Bazuco Frittoli +5 more
doaj +1 more source
Background. The management of children with systemic lupus erythematosus (SLE) is usually associated with lifelong systemic glucocorticoids administration and, thereby, high risk of serious side effects, including steroid-induced diabetes. The belimumab (
Maria I. Kaleda +2 more
doaj +1 more source
Mucocutaneous manifestations in juvenile-onset systemic lupus erythematosus: a review of literature [PDF]
Patients diagnosed with juvenile-onset systemic lupus erythematosus (JSLE) often have skin and oral lesions as part of their presentation. These mucocutaneous lesions, as defined by the American College of Rheumatology (ACR) in 1997, include malar rash, discoid rash, photosensitivity and oral ulcers. It is therefore essential to recognize mucocutaneous
Chiewchengchol, Direkrit +3 more
openaire +2 more sources
The VH gene repertoire of splenic B cells and somatic hypermutation in systemic lupus erythematosus [PDF]
In systemic lupus erythematosus (SLE) it has been hypothesized that self-reactive B cells arise from virgin B cells that express low-affinity, nonpathogenic germline V genes that are cross-reactive for self and microbial antigens, which convert to high ...
Stott, DI +11 more
core +1 more source
Tocilizumab, an anti-interleukin-6 (IL-6) agent, is indicated as a treatment for several autoimmune or inflammatory diseases, including rheumatoid arthritis and juvenile idiopathic arthritis (JIA). IL-6 plays roles in both immune system dysregulation and
Ju-Yang Jung +3 more
doaj +1 more source

