Results 11 to 20 of about 53,292,385 (218)

Musculoskeletal symptoms in juvenile onset systemic lupus erythematosus

Современная ревматология, 2023
In juvenile onset systemic lupus erythematosus (SLE), musculoskeletal involvement is one of the most common manifestations. Musculoskeletal symptoms may be due to disease activity itself, organ damage due to SLE activity, drug exposure, or comorbidities.
M. I. Kaleda, A. N. Arefieva, I. P. Nikishina   +2 more
doaj   +2 more sources

Neuropsychiatric involvement in juvenile-onset systemic lupus erythematosus

Научно-практическая ревматология, 2020
Neuropsychiatric disorders in juvenile-onset systemic lupus erythematosus (SLE) stay in the focus of attention in recent decades due to significant influence of CNS lesions on SLE course in general, necessity to optimize therapeutic interventions and ...
M. I. Kaleda, I. P. Nikishina
doaj   +3 more sources

Neuropsychiatric Involvement in Juvenile-Onset Systemic Lupus Erythematosus [PDF]

Neurology Research International, 2018
Objective. Systemic lupus erythematosus (SLE) is a complex autoimmune disorder characterized by multisystem involvement, including the nervous system.
Mohammad-Amin Khajezadeh, Gholamreza Zamani, Bobak Moazzami, Zahra Nagahi, Mahdie Mousavi-Torshizi, Vahid Ziaee   +5 more
doaj   +3 more sources

Assessment of hematologic indices for diagnosis in juvenile systemic lupus erythematosus

Rheumatology
Introduction The aim was to present effective approaches utilizing novel hematological parameters for early diagnosis of juvenile-onset systemic lupus erythematosus (jSLE).
Gülcan Özomay Baykal, Ebru Oğultekin Vazgeçer, Betül Sözeri   +2 more
doaj   +2 more sources

Quality of life in patients with juvenile-onset systemic lupus erythematosus

Journal of V. N. Karazin Kharkiv National University: Series Medicine
Background. Childhood-onset systemic lupus erythematosus (cSLE) is a rare, multisystem, and potentially life-threatening autoimmune disease with significant comorbidities and the development of a chronic, debilitating condition for the patient.
L.F. Bohmat, N.S. Shevchenko, I.M. Bessonova, T.O. Holovko   +3 more
doaj   +2 more sources

Juvenile-onset systemic lupus erythematosus: different clinical and serological pattern than adult-onset systemic lupus erythematosus

Annals of the Rheumatic Diseases, 2009
To investigate differences in clinical signs and symptoms, and in antinuclear antibodies (ANA), between patients with juvenile-onset and adult-onset systemic lupus erythematosus (SLE).Clinical and serological data of 56 patients with juvenile-onset SLE were compared with data of 194 patients with adult-onset SLE. ANA were determined by line immunoassay
I E A, Hoffman, B R, Lauwerys, F, De Keyser, T W J, Huizinga, D, Isenberg, L, Cebecauer, J, Dehoorne, R, Joos, G, Hendrickx, F, Houssiau, D, Elewaut   +10 more
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The role of hsa_circ_0008945 in juvenile-onset systemic lupus erythematosus

BMC Medical Genomics, 2023
Abstract Background circular RNAs (circRNAs) play a crucial role in many physiological and pathological processes including juvenile-onset systemic lupus erythematosus (JSLE). The aim of this study is to investigate the role of circRNA hsa_circ_0008945 in JSLE and evaluate its significance as diagnosing biomarker.
Qifan Wang, Baiye Xu, Qingmei Zhang, Haidao Wang, Shulian Chen, Tingting Chen, Shishan Liang   +6 more
openaire   +3 more sources

Vasculitis in Juvenile-Onset Systemic Lupus Erythematosus [PDF]

Frontiers in Pediatrics, 2019
Juvenile-onset systemic lupus erythematosus (JSLE) is a rare, heterogeneous multisystem autoimmune disease that can affect any organ, and present with diverse clinical and serological manifestations. Vasculitis can be a feature of JSLE. It more commonly presents as cutaneous vasculitis than visceral vasculitis, which can affect the central nervous ...
Eve M. D. Smith, Eve M. D. Smith, Hanna Lythgoe, Christian M. Hedrich, Christian M. Hedrich   +4 more
openaire   +4 more sources

Rituximab therapy for juvenile-onset systemic lupus erythematosus [PDF]

Pediatric Nephrology, 2007
Rituximab (RTX), an anti-CD20 monoclonal antibody, has been proposed for use in the therapy of systemic lupus erythematosus (SLE). We present the initial long-term experience of the safety and efficacy of rituximab for treatment of SLE in children.
Nwobi, Obioma, Abitbol, Carolyn L., Chandar, Jayanthi, Seeherunvong, Wacharee, Zilleruelo, Gastón   +4 more
openaire   +2 more sources

Juvenile-onset multifocal osteonecrosis in systemic lupus erythematosus

Medicine, 2021
Abstract Rationale: Osteonecrosis (ON) is a devastating illness that leads to bone ischemia and potential joint destruction. Systemic lupus erythematosus (SLE) is a chronic, autoimmune disease, with multi-system involvement which is closely associated with occurrence of ON.
Jin, Wenyuan, Yang, Xinghui, Lu, Meiping
openaire   +2 more sources